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Patients with single\u2010episode HSV\u20102 meningitis were included for comparison.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010seven patients with BRLM (mean annual incidence 1.2\/1,000,000 adults) and 118 with single\u2010episode HSV\u20102 meningitis were included. The progression risk from HSV\u20102 meningitis to BRLM was 22% (95% confidence interval [CI] 15%\u201330%). The proportion of patients with the triad of headache, neck stiffness and photophobia\/hyperacusis was similar between BRLM and single\u2010episode HSV\u20102 meningitis (16\/43 [37%] vs. 46\/103 [45%]; <jats:italic>p<\/jats:italic>\u2009=\u20090.41), whilst the median cerebrospinal fluid leukocyte count was lower in BRLM (221 cells vs. 398 cells; <jats:italic>p<\/jats:italic>\u2009=\u20090.02). Unfavourable functional outcomes (Glasgow Outcome Scale score of 1\u20134) were less frequent in BRLM at all post\u2010discharge follow\u2010up visits. During the study period, 10 (21%) patients with BRLM were hospitalized for an additional recurrence (annual rate 6%, 95% CI 3%\u201312%). The hazard ratio for an additional recurrence was 3.93 (95% CI 1.02\u201315.3) for patients with three or more previous episodes of meningitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Clinical features of BRLM were similar to those of single\u2010episode HSV\u20102 meningitis, whilst post\u2010discharge outcomes were more favourable. Patients with three or more previous episodes of meningitis had higher risk of an additional recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.16081","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T17:29:11Z","timestamp":1696613351000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Benign recurrent lymphocytic meningitis (Mollaret's meningitis) in Denmark: a nationwide cohort study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9352-6093","authenticated-orcid":false,"given":"Pelle Trier","family":"Petersen","sequence":"first","affiliation":[{"name":"Department of Pulmonary and Infectious Diseases Nordsj\u00e6llands Hospital  Hiller\u00f8d Denmark"},{"name":"Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen 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