{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:50:23Z","timestamp":1792507823269,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003495","name":"Hessisches Ministerium f\u00fcr Wissenschaft und Kunst","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003495","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Infection with COVID\u201019 can lead to persistent sequelae, such as fatigue, daytime sleepiness or disturbed sleep, that can remain for more than 12\u2009weeks and that are summarized as post\u2010COVID syndrome. The causes remain unclear. The present study investigated the presence of sleep disorders in patients with post\u2010COVID syndrome using polysomnography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010four patients with post\u2010COVID syndrome and new\u2010onset fatigue and sleepiness after a SARS\u2010CoV2 infection underwent polysomnography in accordance with American Association of Sleep Medicine (AASM) standards as part of their clinical workup. Analysis was performed visually based on AASM criteria (scoring manual version 2.6, 2020).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Polysomnography revealed a sleep efficiency of &lt;80% in 50% of patients and a mean respiratory disturbance index (RDI) of 9.9\u2009\u00b1\u200915.4\/h. Excluding central apneas, 12 patients (35%) had an RDI of \u22655\/h, pointing to obstructive sleep apnea syndrome (OSAS; AASM 2014). Patients with a high RDI were significantly older (<jats:italic>p<\/jats:italic>\u2009=\u20090.01) and showed a trend towards a higher body mass index (<jats:italic>p<\/jats:italic>\u2009=\u20090.08) than patients with a normal RDI but had no other risk factors for OSAS. Six patients agreed to long\u2010term treatment of their OSAS and all reported discontinuation of daytime symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Post\u2010COVID symptoms such as daytime sleepiness, fatigue and memory and concentration problems may in part be a result of reduced sleep efficiency and sleep apnea in a relevant percentage of patients. This possibly treatable cause of the symptoms should be kept in mind in patients presenting with post\u2010COVID syndrome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.16159","type":"journal-article","created":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T18:54:31Z","timestamp":1700679271000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Undiagnosed obstructive sleep apnea syndrome as a treatable cause of new\u2010onset sleepiness in some post\u2010<scp>COVID<\/scp> patients"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8289-480X","authenticated-orcid":false,"given":"Katja","family":"Menzler","sequence":"first","affiliation":[{"name":"Department of Neurology Philipps\u2010University Marburg  Marburg Germany"},{"name":"Center for Mind, Brain and Behavior, CMBB Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Mayr","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Sleep Disorders Centre Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Knake","sequence":"additional","affiliation":[{"name":"Department of Neurology Philipps\u2010University Marburg  Marburg Germany"},{"name":"Center for Mind, Brain and Behavior, CMBB Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Cassel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Sleep Disorders Centre Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Viniol","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Sleep Disorders Centre Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Reitz","sequence":"additional","affiliation":[{"name":"Department of Neurology Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiota\u2010Eleni","family":"Tsalouchidou","sequence":"additional","affiliation":[{"name":"Department of Neurology Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Janzen","sequence":"additional","affiliation":[{"name":"Department of Neurology Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Anschuetz","sequence":"additional","affiliation":[{"name":"Department of Neurology Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Mross","sequence":"additional","affiliation":[{"name":"Department of Neurology Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Koehler","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Sleep Disorders Centre Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa509"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32656-8"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-022-02018-4"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.m2022.0147"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2022.2076901"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408363.2020.1860895"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.14917"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/children9091419"},{"key":"e_1_2_11_10_1","first-page":"439","article-title":"Insomnia and sleep characteristics in post COVID\u201019 related fatigue","volume":"31","author":"Rauwerda N","year":"2022","journal-title":"J Sleep Res"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/mjdrdypu.mjdrdypu_101_21"},{"key":"e_1_2_11_12_1","volume-title":"The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. 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