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Access to novel treatments warrants authoritative treatment recommendations. The Nordic countries have similar, comprehensive health systems, mandatory health registers, and extensive MG research.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>MG experts and patient representatives from the five Nordic countries formed a working group to prepare treatment guidance for MG based on a systematic literature search and consensus meetings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Pyridostigmine represents the first\u2010line symptomatic treatment, while ambenonium and beta adrenergic agonists are second\u2010line options. Early thymectomy should be undertaken if a thymoma, and in non\u2010thymoma patients up to the age of 50\u201365\u2009years if not obtaining remission on symptomatic treatment. Most patients need immunosuppressive drug treatment. Combining corticosteroids at the lowest possible dose with azathioprine is recommended, rituximab being an alternative first\u2010line option. Mycophenolate, methotrexate, and tacrolimus represent second\u2010line immunosuppression. Plasma exchange and intravenous immunoglobulin are used for myasthenic crises and acute exacerbations. Novel complement inhibitors and FcRn blockers are effective and fast\u2010acting treatments with promising safety profiles. Their use depends on local availability, refunding policies, and cost\u2013benefit analyses. Adapted physical training is recommended. Planning of pregnancies with optimal treatment, information, and awareness of neonatal MG is necessary. Social support and adaptation of work and daily life activities are recommended.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Successful treatment of MG rests on timely combination of different interventions. Due to spontaneous disease fluctuations, comorbidities, and changes in life conditions, regular long\u2010term specialized follow\u2010up is needed. Most patients do reasonably well but there is room for further improvement. Novel treatments are promising, though subject to restricted access due to costs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ene.16229","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T03:38:08Z","timestamp":1707277088000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":93,"title":["Generalized myasthenia gravis with acetylcholine receptor antibodies: A guidance for treatment"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6522-5102","authenticated-orcid":false,"given":"Nils Erik","family":"Gilhus","sequence":"first","affiliation":[{"name":"Department of Neurology Haukeland University Hospital  Bergen Norway"},{"name":"Department of Clinical Medicine University of Bergen  Bergen 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