{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T03:10:11Z","timestamp":1781925011613,"version":"3.54.5"},"reference-count":51,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Migraine and sleep disorders share a bidirectional relationship, but little is known about the specific association between migraine and rapid eye movement (REM) sleep behaviour disorder (RBD). The aim was to assess the prevalence of RBD and associated clinical characteristics in adults with migraine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This analysis is part of a cross\u2010sectional survey study conducted at the Headache Centre of the Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin between August 2020 and March 2023. At the end of their regular medical consultation, patients with migraine filled out (1) the validated RBD Screening Questionnaire (RBDSQ), (2) a questionnaire on REM sleep intrusions and (3) the Depression, Anxiety and Stress Scale 21. The primary endpoint was the percentage of patients with a positive RBD screening. A multivariate analysis was performed to identify characteristics independently associated with features of RBD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 751 patients (44.1\u2009\u00b1\u200913.2\u2009years; 87.4% female) with complete RBDSQ were included in this analysis, of which 443 (58.9%) screened positive for RBD. In multivariate analysis, a positive screening for RBD was associated with younger age (odds ratio [OR] 0.9, 95% confidence interval [CI] 0.8\u20130.9 per 10\u2010year increase; <jats:italic>p<\/jats:italic>\u2009=\u20090.005) and with features suggestive of REM sleep intrusions (OR 4.3, 95% CI 1.8\u201310.4; <jats:italic>p<\/jats:italic>\u2009=\u20090.001). Migraine aura remained in the model without reaching statistical significance (OR 1.3, 95% CI 0.9\u20131.8; <jats:italic>p<\/jats:italic>\u2009=\u20090.079).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Symptoms of RBD are frequent in adults with migraine. Further studies including polysomnography are required to confirm this association, and to explore potential common pathophysiological mechanisms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.16403","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T09:53:58Z","timestamp":1720173238000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence and characteristics of rapid eye movement sleep behaviour disorder in adults with migraine: a cross\u2010sectional screening study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8056-8514","authenticated-orcid":false,"given":"Kristin Sophie","family":"Lange","sequence":"first","affiliation":[{"name":"Department of Neurology Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, and Berlin Institute of Health  Berlin 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