{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T03:17:06Z","timestamp":1789787826047,"version":"4.0.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T00:00:00Z","timestamp":1734220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ultra\u2010high\u2010field magnetic resonance imaging (MRI) at a field strength of 7\u2009Tesla (T) has marked a significant milestone in diagnostic imaging since it was approved for clinical use in 2017. Despite the potential to improve image analysis by advances in signal\u2010to\u2010noise ratio, and improved spatial resolution and metabolic imaging, the clinical implementation of 7\u2010T MRI remains limited. Factors that contribute to this limited availability are the high price, the operating costs, the need for specifically educated personnel, and lack of\u00a0evidence of clinical benefit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The aim of this scoping review was to evaluate the evidence of the clinical advantages of 7\u2010T MRI versus MRI at lower field strengths, complementary imaging modalities, and diagnostic standard approaches for neurological and musculoskeletal disorders. We searched MEDLINE, CENTRAL, Embase and Web of Science for this review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 1966 studies, of which 83 were included in our review. Most studies (73 studies, 88%) examined neurological indications, nine studies (11%) examined musculoskeletal indications, and one study reported on peripheral arterial occlusive disease. Of the neuroimaging indications, cerebrovascular diseases were the most frequently investigated (14 studies), followed by multiple sclerosis (13 studies) and epilepsy (11 studies).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The available comparative evidence varied greatly across indications, with the best\u2010documented evidence being for imaging of epilepsy. Risk of bias overall was high, with limitations in blinding information, study design reporting, and patient recruitment details. The identified evidence gaps underscore the need for comparative research to determine appropriate indications and to understand whether the potential diagnostic advantage of 7\u2010T MRI translates to a tangible clinical benefit for patients. Future studies should include clinically relevant patient outcomes that go beyond radiological metrics.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.16557","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T07:56:14Z","timestamp":1734335774000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Assessment of the available evidence for the use of <scp>7\u2010Tesla (T)<\/scp> magnetic resonance imaging (<scp>MRI)<\/scp> in neurological and musculoskeletal disorders, with comparison to <scp>3\u2010T<\/scp> and 1.<scp>5\u2010T MRI<\/scp>: A systematic scoping review"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1062-8622","authenticated-orcid":false,"given":"Piotr","family":"Radojewski","sequence":"first","affiliation":[{"name":"University Institute of Diagnostic and Interventional Neuroradiology Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Translational Imaging Center (TIC) Swiss Institute for Translational and Entrepreneurial Medicine  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Franco","family":"Piredda","sequence":"additional","affiliation":[{"name":"Advanced Clinical Imaging Technology Siemens Healthineers International AG  Lausanne Switzerland"},{"name":"CIBM Centre for Biomedical Imaging  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Bonanno","sequence":"additional","affiliation":[{"name":"University Institute of Diagnostic and Interventional Neuroradiology Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Advanced Clinical Imaging Technology Siemens Healthineers International AG  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl\u2010Olof","family":"L\u00f6vblad","sequence":"additional","affiliation":[{"name":"Division of Diagnostic and Interventional Neuroradiology Geneva University Hospital  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Isabel","family":"Vargas","sequence":"additional","affiliation":[{"name":"Service de Radiologie Clinique des Grangettes\u2010Hirslanden et Facult\u00e9 de M\u00e9decine de l'Universit\u00e9 de Gen\u00e8ve  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reto","family":"Sutter","sequence":"additional","affiliation":[{"name":"Radiology Department Balgrist University Hospital, University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Nanz","sequence":"additional","affiliation":[{"name":"Swiss Center for Musculoskeletal Imaging  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1200-7149","authenticated-orcid":false,"given":"Tanya","family":"Karrer","sequence":"additional","affiliation":[{"name":"University Library University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Salanti","sequence":"additional","affiliation":[{"name":"Institute of Social and Preventive Medicine University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Wiest","sequence":"additional","affiliation":[{"name":"University Institute of Diagnostic and Interventional Neuroradiology Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Translational Imaging Center (TIC) Swiss Institute for Translational and Entrepreneurial Medicine  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,15]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"FDA.FDA news release.https:\/\/www.fda.gov\/news\u2010events\/press\u2010announcements\/fda\u2010clears\u2010first\u20107t\u2010magnetic\u2010resonance\u2010imaging\u2010device"},{"key":"e_1_2_8_3_1","unstructured":"Meduniwien.Press release clinical approval 7T MRI.2024. 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