{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T12:30:11Z","timestamp":1789475411333,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T00:00:00Z","timestamp":1733184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Post\u2010stroke dysphagia is known to have a pronounced effect on mortality and quality of life of stroke patients. Here, we investigate whether this extends to post\u2010stroke fatigue, a major contributor to morbidity after ischemic stroke.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with acute ischemic stroke (recruited consecutively in the STROKE\u2010CARD Registry from 2020 to 2023 at the study center Innsbruck, Austria) were examined for dysphagia via clinical swallowing examination at hospital admission. Post\u2010stroke fatigue was assessed using the Fatigue Severity Scale (FSS) at study specific in person follow\u2010up visits within the first year after ischemic stroke.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 882 ischemic stroke patients (mean age 72.4\u2009\u00b1\u200913.5\u2009years, 36.8% females), dysphagia was present in 22.0% at hospital admission and persisted in 16.2% until hospital discharge. Post\u2010stroke fatigue affected 52.2% of the total cohort during follow\u2010up and was significantly more prevalent among those with dysphagia (68.4% vs. 49.0%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The prevalence of fatigue increased with the severity of dysphagia, with the highest proportion (86.7%) in those with severe dysphagia. After multivariable adjustment for other factors associated with post\u2010stroke fatigue, including age, sex, pre\u2010stroke disability, cognitive impairment, stroke severity, inability to walk at discharge, and need for antidepressants at discharge, dysphagia remained independently associated with post\u2010stroke fatigue during the first year after stroke (odds ratio [OR]: 2.03, 95% confidence interval [CI]: 1.22\u20133.38).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dysphagia is common after ischemic stroke and increases the risk of post\u2010stroke fatigue. Patient\u2010tailored measures are warranted to reduce fatigue after stroke and therefore enhance quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.16570","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T13:55:44Z","timestamp":1733234144000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Dysphagia increases the risk of post\u2010stroke fatigue"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3075-5437","authenticated-orcid":false,"given":"Anel","family":"Karisik","sequence":"first","affiliation":[{"name":"VASCage\u2014Centre on Clinical Stroke Research  Innsbruck Austria"},{"name":"Department of Neurology Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Moelgg","sequence":"additional","affiliation":[{"name":"VASCage\u2014Centre on Clinical Stroke 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