{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T22:53:47Z","timestamp":1774565627954,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:00:00Z","timestamp":1773964800000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100010275","name":"Deutsche Gesellschaft f\u00fcr Muskelkranke","doi-asserted-by":"publisher","award":["Pe5\/2"],"award-info":[{"award-number":["Pe5\/2"]}],"id":[{"id":"10.13039\/501100010275","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017268","name":"Berlin Institute of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012112","name":"Swedish Orphan Biovitrum","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012112","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Monitoring individuals with peripheral neuropathies is challenging due to limited availability and time resources of neurologists, especially for rare genetic forms. This highlights the need for innovative methods to quantify disease severity efficiently and enable telemedical settings. In this study, we explored the feasibility of visual grading of gait disability as a novel approach for remote disease monitoring, using genetic neuropathies (Charcot Marie Tooth Disease, short CMT) as a model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We prospectively evaluated 53 participants with CMT using a battery of clinical examination scores, and patient reported outcome measures (PROMs), as well as semi\u2010standardized sagittal\u2010plane videos of participants walking a 4\u2010m runway for 5\u2009\u00b1\u20092\u2009min cross\u2010sectionally, and developed the Visual Gait Assessment Scale in Polyneuropathy (vGASP) to grade the severity of gait abnormality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three independent raters evaluated the score as easily understandable and quick. The vGASP was internally consistent (inter\u2010class coefficient of 0.9) and valid when correlating with validated clinical outcome measures (Spearman's \u03c1\u2009=\u20090.6\u20130.8).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The vGASP may offer a time\u2010effective solution for remote monitoring of patients in CMT and potentially other gait\u2010affecting polyneuropathies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ene.70532","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T12:05:58Z","timestamp":1774008358000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Validation of a Visual Grading Score of Disease Severity From Gait Videos in Genetic Peripheral Neuropathy"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8711-5526","authenticated-orcid":false,"given":"Helena F.","family":"Pernice","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Neurologie mit Experimenteller Neurologie Charit\u00e9 Universit\u00e4tsmedizin Berlin  Berlin Germany"},{"name":"Berlin Institute of Health at Charit\u00e9 (BIH) Universit\u00e4tsmedizin Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Piazza","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli studi di Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2677-3266","authenticated-orcid":false,"given":"Eleonora","family":"Asaad","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie mit Experimenteller Neurologie Charit\u00e9 Universit\u00e4tsmedizin Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9393-5512","authenticated-orcid":false,"given":"Paul J.","family":"Wetzel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie mit Experimenteller Neurologie Charit\u00e9 Universit\u00e4tsmedizin Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6013-0072","authenticated-orcid":false,"given":"Katrin","family":"Hahn","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie mit Experimenteller Neurologie Charit\u00e9 Universit\u00e4tsmedizin Berlin  Berlin Germany"},{"name":"Berlin Institute of Health at Charit\u00e9 (BIH) Universit\u00e4tsmedizin Berlin  Berlin 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