{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T14:27:46Z","timestamp":1788532066405,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100016033","name":"Waldemar von Frenckells Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007639","name":"Maire Taposen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007639","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007247","name":"Svenska Kulturfonden","doi-asserted-by":"publisher","award":["210836"],"award-info":[{"award-number":["210836"]}],"id":[{"id":"10.13039\/501100007247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008320","name":"Suomen Aivos\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["20240073"],"award-info":[{"award-number":["20240073"]}],"id":[{"id":"10.13039\/501100008320","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS) are related neurovascular conditions, with pregnancy as a shared risk factor. In this study, we aimed to describe shared and distinctive risk factors and outcomes in patients with pregnancy\u2010associated PRES and\/or RCVS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective, nationwide, population\u2010based cohort study, the national healthcare registers were utilized to identify women with PRES and\/or RCVS during pregnancy or puerperium during 1987\u20132016. Subsequent pregnancies, vascular events, and deaths until 2022 were identified. Medical records were reviewed to classify cerebrovascular events and collect clinical details.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 27 patients had pregnancy\u2010associated PRES and\/or RCVS (18 PRES; 5 PRES\u2009+\u2009RCVS; 4 RCVS) during 1987\u20132016, resulting in an incidence of 1.52 per 100,000 (95% Cl 1.02\u20132.18) deliveries. All patients with PRES\u2009\u00b1\u2009RCVS had preeclampsia with severe features during late pregnancy or early puerperium. In contrast, isolated RCVS showed a weaker association to preeclampsia and occurred in late puerperium, with a median puerperal day of 26 (IQR 11\u201345). Altogether, 40.7% of all patients had a stroke, 90.9% of which were hemorrhagic. Preeclampsia was diagnosed in 90.9% of stroke patients. Maternal mortality was 3.7%, whereas perinatal mortality was 7.4%. At 3\u2009months, 92.3% had a good recovery (mRS 0\u20132). During follow\u2010up, stroke recurrence was 3.7% and 33.3% had subsequent uneventful, full\u2010term pregnancies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pregnancy\u2010associated PRES and RCVS are potentially life\u2010threatening, rare conditions that can result in hemorrhagic stroke. PRES\u2009\u00b1\u2009RCVS is strongly associated with preeclampsia with severe features, whereas puerperal RCVS seems to be a separate, later\u2010occurring condition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ene.70615","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:04:42Z","timestamp":1777543482000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Population\u2010Based Study of Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome During Pregnancy and Puerperium"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0698-4824","authenticated-orcid":false,"given":"Vest","family":"Teresa","sequence":"first","affiliation":[{"name":"Department of Neurology University of Helsinki and Helsinki University Hospital  Helsinki 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