{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:16:29Z","timestamp":1783433789991,"version":"3.54.6"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>The safety and effectiveness of mechanical thrombectomy (MT) in patients with cervical artery dissection (CeAD) remain uncertain. This study aimed to evaluate the safety, recanalization rates, and functional outcomes of MT in LVO\u2010AIS patients with and without CeAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective multicenter study based on data prospectively collected from June 2021 to June 2024. CeAD\u2010related LVO\u2010AIS patients treated with MT were compared with matched anterior and posterior circulation AIS patients without CeAD. Primary outcomes included procedural adverse events, recanalization rates, and favorable functional outcomes at 3 months. A meta\u2010analysis of similar studies from 2015 to 2025 was conducted to support generalizability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 1861 LVO\u2010AIS patients, 164 (8.7%) patients had a CeAD. Despite a higher prevalence of tandem occlusion (63.0% vs. 20.0%, SDM: 0.99), CeAD patients showed similar rates of overall procedural adverse events (17.7% vs. 16.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.684), recanalization rates (90.0% vs. 87.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.563), and 90\u2010day favorable functional outcome (59.1% vs. 58.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.917) as compared to non\u2010CeAD patients. Additionally, CeAD patients had a significantly lower mortality rate at 90\u2009days (4.3% vs. 13.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.023). A subgroup analysis of posterior circulation LVO\u2010AIS showed no significant differences in safety and clinical outcomes. Meta\u2010analysis of six studies suggested better MT outcomes in CEAD\u2010related LVO\u2010AIS (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, with\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200960.02% [13.48\u201383.33 95% CI]).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite procedural challenges, this multicenter study has shown that in both anterior and posterior circulation CeAD\u2010related LVO\u2010AIS, MT is as safe as in non\u2010CeAD stroke patients, achieves high recanalization rates, and is associated with similar favorable functional outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ene.70632","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T11:16:59Z","timestamp":1782127019000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mechanical Thrombectomy in Patients With Cervical Artery Dissection: A Multicenter Analysis on Technical, Safety, and Functional Outcomes"],"prefix":"10.1111","volume":"33","author":[{"given":"Francesco","family":"Favruzzo","sequence":"first","affiliation":[{"name":"Stroke Center and Neurosonology Laboratory Azienda Ospedale \u2010 Universit\u00e0 Padova  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marialuisa","family":"Zedde","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center Azienda Unit\u00e0 Sanitaria Locale\u2010IRCCS Di Reggio Emilia  Reggio Emilia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Weis","sequence":"additional","affiliation":[{"name":"IRCCS San Camillo Hospital  Venezia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Pascarella","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Ospedale Santa Maria Della Misericordia  Rovigo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Giossi","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center ASST Cremona Hospital  Cremona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Besana","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology ASST Cremona Hospital  Cremona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Valletta","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center Azienda Ospedaliera Integrata, University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Cappellari","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center Azienda Ospedaliera Integrata, University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetto","family":"Petralia","sequence":"additional","affiliation":[{"name":"Neurovascular Interventional Unit Azienda Ospedaliera Integrata, University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Gentile","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center IRCCS Istituto Delle Scienze Neurologiche Di Bologna, Maggiore Hospital  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1486-4507","authenticated-orcid":false,"given":"Andrea","family":"Zini","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center IRCCS Istituto Delle Scienze Neurologiche Di Bologna, Maggiore Hospital  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Simonetti","sequence":"additional","affiliation":[{"name":"Neuroradiology Unit IRCCS Istituto Scienze Neurologiche Di Bologna, Maggiore Hospital  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Vallone","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Ospedale Civile Di Baggiovara  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Giulia","family":"Mosconi","sequence":"additional","affiliation":[{"name":"Cardiovascular and Emergency Medicine and Stroke Center Azienda Ospedaliera Santa Maria Della Misericordia, University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5483-8795","authenticated-orcid":false,"given":"Maurizio","family":"Paciaroni","sequence":"additional","affiliation":[{"name":"Cardiovascular and Emergency Medicine and Stroke Center Azienda Ospedaliera Santa Maria Della Misericordia, University of Perugia  Perugia Italy"},{"name":"Department of Neurosciences and Rehabilitation University of Ferrara  Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Fiacca","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Azienda Ospedaliera Santa Maria Della Misericordia, University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelia","family":"Zauli","sequence":"additional","affiliation":[{"name":"Department of Neurosciences 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Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Caliandro","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Universit\u00e0 Cattolica Del Sacro Cuore  Rome Italy"},{"name":"Department of Neurology and Stroke Center Fondazione Policlinico Universitario A. Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iacopo","family":"Valente","sequence":"additional","affiliation":[{"name":"Unit of Interventional Neuroradiology Fondazione Policlinico Universitario A. 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