{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:19:44Z","timestamp":1791227984031,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Neuro\u2010Beh\u00e7et syndrome (NBS) is a heterogeneous inflammatory disorder in which venous involvement is well recognized, while intracranial arterial pathology remains insufficiently characterized. Conventional luminal imaging methods are limited in detecting early or isolated arterial wall abnormalities. Vessel wall imaging (VWI) may provide additional insights into arterial involvement in NBS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010nine NBS patients (27 men, 12 women; mean age 38.52\u2009\u00b1\u20099.54\u2009years) underwent intracranial VWI; 16 were imaged during the attack period and 23 during the attack\u2010free period. A total of 1170 artery segments were systematically evaluated for wall thickening patterns and contrast enhancement. VWI findings were analyzed in relation to imaging timing, radiological subtype, MR angiography findings, and EDSS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Vessel wall involvement was found in 16 patients (41%), mainly in the posterior circulation (81%). Concentric wall thickening without enhancement was the most common pattern (80.48%). Vessel wall involvement was significantly more frequent in patients imaged during the attack period compared with those imaged in the attack\u2010free period (68.8% vs. 21.7%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007). Vessel wall enhancement was present only in the attack period (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022). Notably, higher EDSS scores were significantly associated with multisegmental posterior circulation involvement, particularly when \u2265\u20093 segments were affected (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.015;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.024).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Intracranial arterial wall involvement is detectable by VWI in a substantial proportion of NBS patients, predominantly in the posterior circulation with a concentric thickening pattern. These findings suggest that arterial wall pathology may be more common than previously recognized and that VWI provides complementary diagnostic information beyond conventional luminal imaging.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ene.70718","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T07:14:33Z","timestamp":1786086873000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Beyond Venous Inflammation: Vessel Wall Imaging of Intracranial Arteries in Neuro\u2010Beh\u00e7et's Syndrome"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2623-2710","authenticated-orcid":false,"given":"Esra","family":"Kochan Kizilkilic","sequence":"first","affiliation":[{"name":"Department of Neurology University of Health Sciences, Prof. Dr. Cemil Ta\u015fc\u0131o\u011flu City Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bora","family":"Korkmazer","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, Department of Radiology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nursena","family":"Erener","sequence":"additional","affiliation":[{"name":"Department of Neurology Balikesir Atat\u00fcrk City Hospital  Bal\u0131kesir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet Kursat","family":"Karaman","sequence":"additional","affiliation":[{"name":"Department of Radiology Sureyyapasa Chest Diseases and Thoracic Surgery Training Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4124-9032","authenticated-orcid":false,"given":"Abdullah","family":"Arcan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serdar","family":"Arslan","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, Department of Radiology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aksel","family":"Siva","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emire","family":"Seyahi","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, Cerrahpa\u015fa Medical School Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugur","family":"Uygunoglu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6620-8934","authenticated-orcid":false,"given":"Osman","family":"Kizilkilic","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, Department of Radiology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,7]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2017.208"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/sjopt.sjopt_355_24"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(23)02629\u20106"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004150170242"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13010041"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37715"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/anr.1780320217"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2019.01.044"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468\u20101331.2001.00300.x"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.116.013320"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.01102"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247\u2010017\u20103792\u20102"},{"issue":"8697","key":"e_1_2_13_14_1","first-page":"1078","article-title":"Criteria for Diagnosis of Beh\u00e7et's Disease. 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