{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T20:01:15Z","timestamp":1789416075744,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,5,3]],"date-time":"2013-05-03T00:00:00Z","timestamp":1367539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J Oral Sciences"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p>The aim of this study was to compare changes in dental arch morphology between patients with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>rouzon syndrome or <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pert syndrome and controls. Children between 4 and 14\u00a0yr of age with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>rouzon syndrome (<jats:italic>n\u00a0<\/jats:italic>=\u00a040) or <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pert syndrome (<jats:italic>n\u00a0<\/jats:italic>=\u00a028) were compared with non\u2010syndromic controls (<jats:italic>n\u00a0<\/jats:italic>=\u00a0457) in terms of arch widths, depths, and length dimensions. Multilevel statistical modeling techniques were used to evaluate changes over time. Dental arch dimensions were found to be smaller in patients with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>rouzon syndrome or <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pert syndrome compared with control subjects. Maxillary intercanine width for patients with <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pert syndrome were increased, whilst other arch width variables showed no change. Patients with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>rouzon syndrome showed increases in maxillary intercanine width, whilst intermolar width showed no change over time. Dental arch dimensions in syndromic patients were thus found to be consistently smaller than in control subjects between 4 and 14\u00a0yr of age, implying that patients with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>rouzon syndrome and <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pert syndrome had a diminished growth potential.<\/jats:p>","DOI":"10.1111\/eos.12051","type":"journal-article","created":{"date-parts":[[2013,5,3]],"date-time":"2013-05-03T12:19:01Z","timestamp":1367583541000},"page":"319-327","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["A longitudinal study of dental arch morphology in children with the syndrome of <scp>C<\/scp>rouzon or <scp>A<\/scp>pert"],"prefix":"10.1111","volume":"121","author":[{"given":"Jacobus H.","family":"Reitsma","sequence":"first","affiliation":[{"name":"Department of Orthodontics Academic Centre for Dentistry Amsterdam (ACTA) Universiteit van Amsterdam and Vrije Universiteit Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poejan","family":"Elmi","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Academic Centre for Dentistry Amsterdam (ACTA) Universiteit van Amsterdam and Vrije Universiteit Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin M.","family":"Ongkosuwito","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Sophia Children's Hospital Erasmus MC Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H.","family":"Buschang","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Baylor College of Dentistry The Texas A&amp;M University System Health Science Center Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birte","family":"Prahl\u2010Andersen","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Academic Centre for Dentistry Amsterdam (ACTA) Universiteit van Amsterdam and Vrije Universiteit Amsterdam The Netherlands"},{"name":"Department of Orthodontics Sophia Children's Hospital Erasmus MC Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(96)80011-7"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844318109103433"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844318209026215"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(84)90087-3"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/000163598428275"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1597\/12\u2010180"},{"key":"e_1_2_5_8_1","first-page":"195","article-title":"Dental agenesis patterns in Crouzon syndrome","volume":"35","author":"Stavropoulos D","year":"2011","journal-title":"Swed Dent J"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2011.00821.x"},{"key":"e_1_2_5_10_1","volume-title":"The dentition of the growing child","author":"Moorrees CFA","year":"1959"},{"key":"e_1_2_5_11_1","first-page":"911","article-title":"Multivariate patterns of variation in dental arch morphology of French\u2010Canadians","volume":"59","author":"Buschang PH","year":"1987","journal-title":"Hum Biol"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjn124"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(69)90037-2"},{"key":"e_1_2_5_14_1","first-page":"6","article-title":"Changes in arch width. 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