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The aim of this study was to determine the prevalence of oral yeasts in oral lichen planus (OLP) patients and control subjects, and to perform a multiple logistic regression analysis to identify factors that influence oral <jats:italic>Candida<\/jats:italic> infection in OLP patients. In this cross\u2010sectional study, 90 new patients with OLP and 90 sex\u2010 and age\u2010matched control subjects with no mucosal lesions were interviewed about their health status, use of medication, and smoking and alcohol habits. Swab and unstimulated whole saliva samples were collected and salivary <jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content> was measured. A positive <jats:italic>Candida<\/jats:italic> culture was more prevalent among OLP patients (48.9%) than among control subjects (26.7%). <jats:italic>Candida albicans<\/jats:italic> was the most frequently isolated species in both groups. By logistic regression analysis, unstimulated whole salivary flow rates of 0.11\u20130.24\u00a0ml\u00a0min<jats:sup>\u22121<\/jats:sup> (OR\u00a0=\u00a05.90) and 0.25\u20130.32\u00a0ml\u00a0min<jats:sup>\u22121<\/jats:sup> (OR\u00a0=\u00a03.51) and benzodiazepine anxiolytics intake (OR\u00a0=\u00a08.30) were independently associated with the presence of <jats:italic>Candida<\/jats:italic> among OLP patients. Age, denture wearing, levels of dentition, decreased salivary <jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content>, antihypertensive drugs, and alcohol consumption were not associated with oral <jats:italic>Candida<\/jats:italic> infection in OLP patients. The results indicate that data on benzodiazepine anxiolytics intake and evaluation of unstimulated whole salivary flow rate should be considered as part of the clinical evaluation to identify OLP patients at risk for <jats:italic>Candida<\/jats:italic> infection.<\/jats:p>","DOI":"10.1111\/eos.12073","type":"journal-article","created":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T12:54:52Z","timestamp":1373979292000},"page":"427-433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Unstimulated whole salivary flow rate and anxiolytics intake are independently associated with oral <i><scp>C<\/scp>andida<\/i> infection in patients with oral lichen planus"],"prefix":"10.1111","volume":"121","author":[{"given":"Marija","family":"Bokor\u2010Bratic","sequence":"first","affiliation":[{"name":"Dental Clinic Faculty of Medicine University of Novi Sad Novi Sad 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