{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T05:52:53Z","timestamp":1775022773971,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T00:00:00Z","timestamp":1424044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J Oral Sciences"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>Zinc (Zn) reduces the formation of volatile sulphur compounds (<jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content>s) associated with oral malodour. Although strontium (Sr) is included in some products for reducing dental hypersensitivity, it may also have anti\u2010halitosis properties. This randomized, double\u2010blind, cross\u2010over clinical study compared the anti\u2010<jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> effect of brushing with commercial toothpastes and rinses containing Zn and Sr. The volunteers (<jats:italic>n<\/jats:italic>\u00a0=\u00a030) either brushed\/rinsed with\/without tongue brushing using Zn\u2010containing toothpaste\/rinse, Sr\u2010containing toothpaste\/rinse, or placebo (control). Volatile sulphur compounds [hydrogen sulphide (H<jats:sub>2<\/jats:sub>S) and methyl mercaptan (<jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content><jats:sub>3<\/jats:sub><jats:styled-content style=\"fixed-case\">SH<\/jats:styled-content>)] were measured, in morning breath, using gas chromatography. The anti\u2010<jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> effects of the test toothpastes and test rinses were significantly better than the anti\u2010<jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> effects of the respective controls. Toothbrushing with test toothpastes gave median reductions, compared with the control, of 70% for H<jats:sub>2<\/jats:sub>S and 55\u201357% for <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content><jats:sub>3<\/jats:sub><jats:styled-content style=\"fixed-case\">SH<\/jats:styled-content>. Rinsing with the Sr\u2010 and Zn\u2010containing solutions had the same anti\u2010<jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> effect as toothbrushing and tooth\u2010 and tongue brushing with the Sr\u2010 and Zn\u2010containing toothpastes. Zinc\u2010containing rinse resulted in a significantly higher median salivary level of Zn compared with brushing with Zn\u2010containing toothpaste, although this effect did not correlate with the anti\u2010<jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> effect. It can be concluded that the Sr\u2010\u00a0and Zn\u2010containing toothpastes and the Zn\u2010 and Sr\u2010containing rinses, when used in the evening, are equally effective in reducing morning\u2010breath VSCs the following day.<\/jats:p>","DOI":"10.1111\/eos.12169","type":"journal-article","created":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T10:53:02Z","timestamp":1424083982000},"page":"72-79","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Short\u2010term effect of strontium\u2010 and zinc\u2010containing toothpastes and mouthrinses on volatile sulphur compounds in morning breath: a randomized, double\u2010blind, cross\u2010over clinical study"],"prefix":"10.1111","volume":"123","author":[{"given":"L\u00e9o G.","family":"Soares","sequence":"first","affiliation":[{"name":"Department of Periodontology Universidade Estadual do Rio Rio de Janeiro\u2010RJ Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grazyna","family":"Jonski","sequence":"additional","affiliation":[{"name":"Clinical Research Laboratory Faculty of Dentistry University of Oslo Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo M. 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