{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:26:52Z","timestamp":1761744412161},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,9,27]],"date-time":"2016-09-27T00:00:00Z","timestamp":1474934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J Oral Sciences"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:p>The aim of this study was to explore the association between the presence of comorbidities and the pain experience in individual patients with temporomandibular disorder (<jats:styled-content style=\"fixed-case\">TMD<\/jats:styled-content>). This clinical trial comprised 112 patients with <jats:styled-content style=\"fixed-case\">TMD<\/jats:styled-content> pain. For all participants the presence of the following comorbid factors was assessed: pain in the neck; somatization; impaired sleep; and depression. Pain experience was evaluated using the McGill Pain Questionnaire (<jats:styled-content style=\"fixed-case\">MPQ<\/jats:styled-content>). For each subject the TMD\u2010pain experience was assessed for three dimensions \u2013 sensory, affective, and evaluative \u2013 as specified in the <jats:styled-content style=\"fixed-case\">MPQ<\/jats:styled-content>. The association between comorbid factors and these three dimensions of <jats:styled-content style=\"fixed-case\">TMD<\/jats:styled-content>\u2010pain experience was then evaluated using linear regression models. Univariable regression analyses showed that all comorbid factors, except for one factor, were positively associated with the level of pain, as rated by the sensory description of pain, the affective component of pain, and the evaluative experience of pain. The multivariable regression analyses showed that for all <jats:styled-content style=\"fixed-case\">MPQ<\/jats:styled-content> dimensions, depression showed the strongest associations with pain experience. It was found that in the presence of comorbid disorders, patients with <jats:styled-content style=\"fixed-case\">TMD<\/jats:styled-content> experience elevated levels of <jats:styled-content style=\"fixed-case\">TMD<\/jats:styled-content> pain. This information should be taken into consideration in the diagnostic process, as well as in the choice of treatment.<\/jats:p>","DOI":"10.1111\/eos.12295","type":"journal-article","created":{"date-parts":[[2016,9,27]],"date-time":"2016-09-27T10:51:27Z","timestamp":1474973487000},"page":"459-464","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Is the experience of pain in patients with temporomandibular disorder associated with the presence of comorbidity?"],"prefix":"10.1111","volume":"124","author":[{"given":"Corine M.","family":"Visscher","sequence":"first","affiliation":[{"name":"Department of Oral Kinesiology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and VU University Amsterdam MOVE Research Institute Amsterdam Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin A.","family":"van Wesemael\u2010Suijkerbuijk","sequence":"additional","affiliation":[{"name":"Department of Oral Kinesiology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and VU University Amsterdam MOVE Research Institute Amsterdam Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Lobbezoo","sequence":"additional","affiliation":[{"name":"Department of Oral Kinesiology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and VU University Amsterdam MOVE Research Institute Amsterdam Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9,27]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"127","volume-title":"Orofacial pain: guidelines for assessment, diagnosis, and management","author":"Leeuw R","year":"2013"},{"key":"e_1_2_5_3_1","first-page":"49","article-title":"The changing field of temporomandibular disorders: what dentists need to know","volume":"75","author":"Klasser GD","year":"2009","journal-title":"J Can Dent Assoc"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-8-46"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2010.12.024"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0722.2001.00996.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0722.2001.00008.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1192\/S0007125000298474"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e31820215f5"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2011.08.007"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(98)00171-7"},{"key":"e_1_2_5_12_1","first-page":"275","article-title":"Why are the diagnosis and management of orofacial pain so challenging?","volume":"75","author":"Sessle BJ","year":"2009","journal-title":"J Can Dent Assoc"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.11607\/jop.1151"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.11607\/jop.1121"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01480.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-199012000-00002"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(75)90044-5"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(87)90027-3"},{"key":"e_1_2_5_19_1","first-page":"669","article-title":"The Dutch version of the McGill pain questionnaire: a reliable pain questionnaire","volume":"139","author":"Van der Kloot WA","year":"1995","journal-title":"Ned Tijdschr Geneeskd"},{"key":"e_1_2_5_20_1","volume-title":"SCL\u201090, Handleiding bij een Multidimensionele Psychopathologie\u2010indicator","author":"Arindell WA","year":"2003"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.128.3.280"},{"key":"e_1_2_5_22_1","first-page":"39","article-title":"A reliability study of dynamic and static pain tests in temporomandibular disorder patients","volume":"21","author":"Visscher CM","year":"2007","journal-title":"J Orofac Pain"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2005.01.012"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2004.06.003"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2013.03.004"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(76)90113-5"},{"key":"e_1_2_5_27_1","first-page":"67","article-title":"Relationship between MPQ and VAS in 962 patients. 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