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The aim of this study was to investigate if the salivary glands as a component of the mucosal immune system are involved in CD, leading to sialadenitis and salivary gland dysfunction and associated oral manifestations. Twenty patients with CD aged 49.2 (SD 15.5 years) and 20 age\u2010 and gender\u2010matched healthy controls underwent an interview regarding general and oral health, serological analysis, a clinical oral examination including bitewing radiographs, <jats:italic>Candida<\/jats:italic> smear, assessment of salivary mutans streptococci and lactobacilli levels, unstimulated and chewing\u2010stimulated whole and parotid saliva flow rates, analysis of secretory IgA, and a labial salivary gland biopsy. Xerostomia, mucosal lesions, dry\/cracked lips and focal lymphocytic sialadenitis were more prevalent and extensive in patients with CD than in healthy controls. Moreover, the patients had less gingival inflammation and higher whole saliva flow rates than the healthy controls, but did not differ regarding dental health and levels of cariogenic bacteria and <jats:italic>Candida<\/jats:italic>. The major salivary gland function appears unaffected, contributing to maintenance of a balanced microbiota and oral health in CD patients. Xerostomia and labial dryness may be related to minor salivary gland inflammation and subsequent impaired mucosal lubrication.<\/jats:p>","DOI":"10.1111\/eos.12861","type":"journal-article","created":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T10:18:23Z","timestamp":1646475503000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Salivary gland involvement and oral health in patients with coeliac disease"],"prefix":"10.1111","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6259-2548","authenticated-orcid":false,"given":"Jason","family":"Liu","sequence":"first","affiliation":[{"name":"Section for Oral Medicine\/Oral Biology and Immunopathology Department of Odontology Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen 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