{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T18:51:15Z","timestamp":1783536675105,"version":"3.55.0"},"reference-count":59,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J Oral Sciences"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This in vitro study evaluated fluoride release and\n                    <jats:italic>Streptococcus mutans<\/jats:italic>\n                    biofilm formation on four types of dental sealants: a giomer, resin\u2010modified glass ionomer, compomer, and a fluoride\u2010free composite (control). Discs were prepared as per the manufacturers\u2019 instructions, and they were placed in tubes containing ultrapure water. Fluoride release was measured after 2, 7, and 30 days using ion chromatography, and biofilm formation was analyzed via scanning electron microscopy (SEM). A repeated\u2010measures linear mixed model with log transformation and Bonferroni\u2010corrected post\u2010hoc tests was applied. The resin\u2010modified glass ionomer showed the highest fluoride release, followed by the giomer, with increasing values over time. Compomer and the fluoride\u2010free composite exhibited low, stable fluoride levels. SEM confirmed\n                    <jats:italic>S. mutans<\/jats:italic>\n                    biofilm on all materials. These findings highlight distinct fluoride release profiles and suggest that materials with higher fluoride release may offer improved long\u2010term protection against cariogenic biofilm formation.\n                  <\/jats:p>","DOI":"10.1111\/eos.70034","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T05:20:17Z","timestamp":1753766417000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of\n                    <i>Streptococcus mutans<\/i>\n                    biofilm formation on fluoride\u2010releasing materials used as pit and fissure sealants"],"prefix":"10.1111","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4306-1658","authenticated-orcid":false,"given":"Patr\u00edcia da S. L.","family":"Pereira da Silva","sequence":"first","affiliation":[{"name":"School of Dentistry Fluminense Federal University  Niter\u00f3i Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8082-656X","authenticated-orcid":false,"given":"Mariana da Silva","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Biomass Study and Water Management Center Fluminense Federal University  Niter\u00f3i Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5179-1146","authenticated-orcid":false,"given":"Anderson","family":"de Ara\u00fajo Rocha","sequence":"additional","affiliation":[{"name":"Biomass Study and Water Management Center Fluminense Federal University  Niter\u00f3i Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2440-7844","authenticated-orcid":false,"given":"Rosana Rocha","family":"Barros","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Parasitology Fluminense Federal University  Niter\u00f3i Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4388-6310","authenticated-orcid":false,"given":"Lucio Sousa","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"School of Dentistry Est\u00e1cio de S\u00e1 University Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6878-7482","authenticated-orcid":false,"given":"M\u00f4nica Almeida","family":"Tostes","sequence":"additional","affiliation":[{"name":"School of Dentistry Fluminense Federal University  Niter\u00f3i Rio de Janeiro 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