{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T11:44:08Z","timestamp":1791027848714,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,7]],"date-time":"2013-01-07T00:00:00Z","timestamp":1357516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The benign occipital epilepsies of childhood include <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>anayiotopoulos and <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>astaut syndromes; a third syndrome, idiopathic photosensitive occipital epilepsy may also begin in childhood or adolescence. We describe siblings with occipital epilepsy characterized by refractory, frequent, brief visual seizures and normal magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>). Electroencephalography (<jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>) with functional <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> (fMRI) supports localization of interictal epileptiform activity to the occipital lobes. Our hypothesis is that the siblings share a genetic focal epilepsy arising from a localized occipital network. Although they share many features of <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>astaut syndrome, their refractory ongoing seizures in adolescence is unusual and likely due to underlying genetic determinants.<\/jats:p>","DOI":"10.1111\/epi.12076","type":"journal-article","created":{"date-parts":[[2013,1,7]],"date-time":"2013-01-07T14:14:58Z","timestamp":1357568098000},"source":"Crossref","is-referenced-by-count":5,"title":["Siblings with refractory occipital epilepsy showing localized network activity on <scp>EEG<\/scp>\u2010f<scp>MRI<\/scp>"],"prefix":"10.1111","volume":"54","author":[{"given":"Patrick W.","family":"Carney","sequence":"first","affiliation":[{"name":"Epilepsy Research Centre Austin Health Department of Medicine University of Melbourne Heidelberg Victoria Australia"},{"name":"Brain Research Institute Florey Neuroscience Institutes Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Simon","family":"Harvey","sequence":"additional","affiliation":[{"name":"Children's Neuroscience Centre and Department of Paediatrics The University of Melbourne Royal Children's Hospital Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel F.","family":"Berkovic","sequence":"additional","affiliation":[{"name":"Epilepsy Research Centre Austin Health Department of Medicine University of Melbourne Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme D.","family":"Jackson","sequence":"additional","affiliation":[{"name":"Brain Research Institute Florey Neuroscience Institutes Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid E.","family":"Scheffer","sequence":"additional","affiliation":[{"name":"Epilepsy Research Centre Austin Health Department of Medicine University of Melbourne Heidelberg Victoria Australia"},{"name":"Children's Neuroscience Centre and Department of Paediatrics The University of Melbourne Royal Children's Hospital Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2010.02522.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181f11c06"},{"key":"e_1_2_7_4_1","first-page":"227","volume-title":"Epileptic syndromes in infancy, childhood and adolescence","author":"Covanis A","year":"2005"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/155005948201300102"},{"key":"e_1_2_7_6_1","first-page":"47","volume-title":"Migraine and epilepsy","author":"Gastaut H","year":"1987"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1995.tb01631.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2006.00626.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/088307380001500810"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn162"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh211"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn138"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fepi.12076","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.12076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T04:50:58Z","timestamp":1698641458000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.12076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,7]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1111\/epi.12076"],"URL":"https:\/\/doi.org\/10.1111\/epi.12076","archive":["Portico"],"relation":{},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,7]]}}}