{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T08:06:22Z","timestamp":1769501182032,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"s9","license":[{"start":{"date-parts":[[2013,12,12]],"date-time":"2013-12-12T00:00:00Z","timestamp":1386806400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Patients with tumor\u2010related epilepsy (<jats:styled-content style=\"fixed-case\">TRE<\/jats:styled-content>) represent an important proportion of epilepsy surgery cases. Recently established independent negative predictors of postoperative seizure outcome are long duration of epilepsy, presence of generalized tonic\u2013clonic seizures, and incomplete tumor resection. In temporal lobe cases, additional hippocampectomy or corticectomy may further improve outcome. Invasive electroencephalography (<jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>) recordings (<jats:styled-content style=\"fixed-case\">IEEG<\/jats:styled-content>) may be indicated to guide the resection by defining eloquent cortex (EC) or to determine the extent of potentially magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>)\u2013negative epileptogenic tissue. In fact, invasive recordings are reportedly used in up to 10% of patients who are undergoing epilepsy surgery for <jats:styled-content style=\"fixed-case\">TRE<\/jats:styled-content>. Following careful consideration of the concepts underlying epilepsy surgery, the current use of <jats:styled-content style=\"fixed-case\">IEEG<\/jats:styled-content>, and the predictors of outcome in extratemporal and temporal tumors in <jats:styled-content style=\"fixed-case\">TRE<\/jats:styled-content>, we postulate the following&gt; (1) In patients with extratemporal <jats:styled-content style=\"fixed-case\">TRE<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IEEG<\/jats:styled-content> is necessary only if the <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> lesion (and if feasible a rim around it) cannot be completely resected because of adjacent or overlapping <jats:styled-content style=\"fixed-case\">EC<\/jats:styled-content>. In these cases, <jats:styled-content style=\"fixed-case\">EC<\/jats:styled-content> should be mapped to determine its relationships to the lesion, the irritative, and seizure\u2010onset zones in order to maximize the extent of the lesionectomy. (2) In patients with nondominant temporal <jats:styled-content style=\"fixed-case\">TRE<\/jats:styled-content>, data suggest that if epileptogenic tumors (<jats:styled-content style=\"fixed-case\">ET<\/jats:styled-content>s) are encroaching on mesial temporal structures, if epilepsy duration is long, and seizures are frequent and disabling, these structures should be included in the resection. (3) In patients with dominant temporal <jats:styled-content style=\"fixed-case\">TRE<\/jats:styled-content>, we suggest leaving the mesial structures in place if they are functionally and structurally intact and to consider resecting these structures only if they are structurally and functionally abnormal. There is insufficient evidence justifying the use of <jats:styled-content style=\"fixed-case\">IEEG<\/jats:styled-content> to define the extent of the epileptogenic zone in such cases. This should be reserved for cases where an initial lesionectomy has failed.<\/jats:p>","DOI":"10.1111\/epi.12446","type":"journal-article","created":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T04:55:40Z","timestamp":1386910540000},"page":"61-65","source":"Crossref","is-referenced-by-count":24,"title":["Invasive <scp>EEG<\/scp> studies in tumor\u2010related epilepsy: When are they indicated and with what kind of electrodes?"],"prefix":"10.1111","volume":"54","author":[{"given":"Felix","family":"Rosenow","sequence":"first","affiliation":[{"name":"Department of Neurology Epilepsy Center Hessen University Hospital Marburg and Philipps\u2010University Marburg Marburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Menzler","sequence":"additional","affiliation":[{"name":"Department of Neurology Epilepsy Center Hessen University Hospital Marburg and Philipps\u2010University Marburg Marburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1586\/14737175.8.6.941"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2012.03633.x"},{"issue":"3","key":"e_1_2_9_4_1","first-page":"280","article-title":"Surgical management of temporal lobe tumor\u2010related epilepsy in children","volume":"102","author":"Cataltepe O","year":"2005","journal-title":"J Neurosurg"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.2000.tb01536.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03269.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e31823c3a30"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1999.tb00856.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.1.97"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015761507357"},{"key":"e_1_2_9_11_1","unstructured":"L\u00fcdersH. 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