{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:22:47Z","timestamp":1785770567261,"version":"3.56.0"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,2,22]],"date-time":"2014-02-22T00:00:00Z","timestamp":1393027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Some patients with <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>turge\u2010<jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>eber syndrome (<jats:styled-content style=\"fixed-case\">SWS<\/jats:styled-content>) need epilepsy surgery for adequate seizure control and prevention of psychomotor deterioration. The majority of patients with <jats:styled-content style=\"fixed-case\">SWS<\/jats:styled-content> have leptomeningeal angioma located over the temporal, parietal, and occipital lobes. We applied posterior quadrant disconnection surgery for this type of <jats:styled-content style=\"fixed-case\">SWS<\/jats:styled-content> with intractable seizure. We evaluated the efficacy of this procedure in seizure control and psychomotor development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ten patients who were surgically treated using the posterior quadrantectomy (<jats:styled-content style=\"fixed-case\">PQT<\/jats:styled-content>) were enrolled in this study. Surgical outcome was analyzed as seizure\u2010free or not at 2\u00a0years after surgery. Psychomotor development was evaluated by the scores of mental developmental index (<jats:styled-content style=\"fixed-case\">MDI<\/jats:styled-content>) and psychomotor developmental index (<jats:styled-content style=\"fixed-case\">PDI<\/jats:styled-content>) in the Bayley Scales of Infant Development <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> preoperatively, and at 6 and 12 months after the <jats:styled-content style=\"fixed-case\">PQT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eight of 10 patients were seizure\u2010free. Patients without complete elimination of the angiomatous areas had residual seizures. Average <jats:styled-content style=\"fixed-case\">MDI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PDI<\/jats:styled-content> scores before the surgery were 64.8 and 71.6, respectively. Scores of <jats:styled-content style=\"fixed-case\">MDI<\/jats:styled-content> at 6 and 12 months after the <jats:styled-content style=\"fixed-case\">PQT<\/jats:styled-content> in seizure\u2010free patients were 80.5 and 84.5, respectively (p\u00a0&lt;\u00a00.01). <jats:styled-content style=\"fixed-case\">PDI<\/jats:styled-content> scores at these postoperative intervals were 87.3 and 86.4, respectively (p\u00a0&lt;\u00a00.05). Patients with residual seizures did not improve in either <jats:styled-content style=\"fixed-case\">MDI<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">PDI<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">PQT<\/jats:styled-content> achieved good seizure control and improved psychomotor development in patients with <jats:styled-content style=\"fixed-case\">SWS<\/jats:styled-content>. The complete deafferentation of angiomatous areas is required for seizure\u2010free results and psychomotor developmental improvement.<\/jats:p><jats:p>A PowerPoint slide summarizing this article is available for download in the Supporting Information section <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.12547\/supinfo\">here<\/jats:ext-link>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/epi.12547","type":"journal-article","created":{"date-parts":[[2014,2,24]],"date-time":"2014-02-24T17:53:44Z","timestamp":1393264424000},"page":"683-689","source":"Crossref","is-referenced-by-count":44,"title":["Posterior quadrant disconnection surgery for <scp>S<\/scp>turge\u2010<scp>W<\/scp>eber syndrome"],"prefix":"10.1111","volume":"55","author":[{"given":"Hidenori","family":"Sugano","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Juntendo University Tokyo 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