{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:29:12Z","timestamp":1761823752522},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,7,21]],"date-time":"2015-07-21T00:00:00Z","timestamp":1437436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The objective of this study was to determine the prevalence of seizures in children with tectal gliomas and to determine if there are common clinical, electroencephalography (<jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>), or radiologic findings that predict risk of seizures in these patients. We conducted a retrospective review of all patients with tectal gliomas over a 22\u2010year period at a single institution. Data extraction included sex, age at presentation of tectal glioma and age of presentation with seizures, magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) findings, seizure frequency and semiology, and <jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content> findings. We identified 79 patients, 66 of whom had adequate imaging and clinical data for further analysis. Eight patients (12.1%) had a history of seizures. Three patients had a clear symptomatic cause of seizures. Three patients were diagnosed with a tectal glioma as an incidental finding after a first seizure. One patient had a history of febrile convulsions. One patient had a generalized seizure 5\u00a0years after presenting with macrocephaly. Although the risk of seizure in children with known tectal glioma was relatively high, we did not identify specific clinical, radiologic, <jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>, or <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> features that are predictive of increased risk. Thus, in children with tectal gliomas who have seizures, alternative causes for the seizures must be sought.<\/jats:p>","DOI":"10.1111\/epi.13080","type":"journal-article","created":{"date-parts":[[2015,7,21]],"date-time":"2015-07-21T07:51:43Z","timestamp":1437465103000},"source":"Crossref","is-referenced-by-count":5,"title":["Risk of seizures in children with tectal gliomas"],"prefix":"10.1111","volume":"56","author":[{"given":"Gabriel","family":"Dabscheck","sequence":"first","affiliation":[{"name":"Department of Neurology Boston Children's Hospital Boston Massachusetts U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay P.","family":"Prabhu","sequence":"additional","affiliation":[{"name":"Department of Radiology Boston Children's Hospital Boston Massachusetts U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter E.","family":"Manley","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology Boston Children's Hospital Boston Massachusetts U.S.A"},{"name":"Dana\u2010Farber\/Boston Children's Cancer and Blood Disorders Center Boston Massachusetts U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliana","family":"Goumnerova","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber\/Boston Children's Cancer and Blood Disorders Center Boston Massachusetts U.S.A"},{"name":"Department of Neurosurgery Boston Children's Hospital Boston Massachusetts U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole J.","family":"Ullrich","sequence":"additional","affiliation":[{"name":"Department of Neurology Boston Children's Hospital Boston Massachusetts U.S.A"},{"name":"Dana\u2010Farber\/Boston Children's Cancer and Blood Disorders Center Boston Massachusetts U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7,21]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"977","article-title":"Tectal tumors of childhood: clinical and imaging follow\u2010up","volume":"19","author":"Poussaint TY","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000069823"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2004.12.014"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32833e996c"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1059-1311(03)00083-9"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2003.59102.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410400115"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073809342491"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.01.202"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2005.03.007"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000052089"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fepi.13080","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fepi.13080","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.13080","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T10:54:18Z","timestamp":1696330458000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.13080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,21]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1111\/epi.13080"],"URL":"https:\/\/doi.org\/10.1111\/epi.13080","archive":["Portico"],"relation":{},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,21]]}}}