{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T22:11:01Z","timestamp":1783203061201,"version":"3.54.6"},"reference-count":9,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T00:00:00Z","timestamp":1464048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007321","name":"Finding A Cure for Epilepsy and Seizures","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1 TR000038"],"award-info":[{"award-number":["UL1 TR000038"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Sudden unexpected death in epilepsy (<jats:styled-content style=\"fixed-case\">SUDEP<\/jats:styled-content>) is the most common cause of epilepsy\u2010related mortality. We hypothesized that electrocardiography (<jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content>) features may distinguish <jats:styled-content style=\"fixed-case\">SUDEP<\/jats:styled-content> cases from living subjects with epilepsy. Using a matched case\u2013control design, we compared <jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> studies of 12 consecutive cases of <jats:styled-content style=\"fixed-case\">SUDEP<\/jats:styled-content> over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown\/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (<jats:styled-content style=\"fixed-case\">QRS<\/jats:styled-content> \u2265110 msec), abnormal ventricular conduction pattern (<jats:styled-content style=\"fixed-case\">QRS<\/jats:styled-content> &lt;110 msec, morphology of incomplete right or left bundle branch block or intraventricular conduction delay), early repolarization, and features of inherited cardiac channelopathies were assessed. Abnormal ventricular conduction diagnosis and pattern distinguished <jats:styled-content style=\"fixed-case\">SUDEP<\/jats:styled-content> cases from matched controls. Abnormal ventricular conduction diagnosis was present in two cases and no controls. Abnormal ventricular conduction pattern was more common in cases than controls (58% vs. 18%, p = 0.04). Early repolarization was similarly prevalent in cases and controls, but the overall prevalence exceeded that of published community\u2010based cohorts.<\/jats:p>","DOI":"10.1111\/epi.13411","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T19:40:01Z","timestamp":1464118801000},"source":"Crossref","is-referenced-by-count":36,"title":["Electrocardiographic features of sudden unexpected death in epilepsy"],"prefix":"10.1111","volume":"57","author":[{"given":"Janice Y.","family":"Chyou","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Medicine Columbia University Medical Center New York New York U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Friedman","sequence":"additional","affiliation":[{"name":"Division of Epilepsy Department of Neurology New York University School of Medicine New York New York U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Cerrone","sequence":"additional","affiliation":[{"name":"Leon H. Charney Division of Cardiology New York University School of Medicine New York New York U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Slater","sequence":"additional","affiliation":[{"name":"Leon H. Charney Division of Cardiology New York University School of Medicine New York New York U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Guo","sequence":"additional","affiliation":[{"name":"Division of Biostatistics Department of Population Health New York University School of Medicine New York New York U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Taupin","sequence":"additional","affiliation":[{"name":"Department of Medicine New York University School of Medicine New York New York U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"O'Rourke","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Medical Center New York New York U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia G.","family":"Priori","sequence":"additional","affiliation":[{"name":"Leon H. Charney Division of Cardiology New York University School of Medicine New York New York U.S.A"},{"name":"Molecular Cardiology IRCCS Salvatore Maugeri Foundation Pavia Italy"},{"name":"Department of Molecular Medicine University of Pavia  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orrin","family":"Devinsky","sequence":"additional","affiliation":[{"name":"Division of Epilepsy Department of Neurology New York University School of Medicine New York New York U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1010481"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.55.6.857"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03358.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.013"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa071968"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2013.05.014"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.04.003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000314"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2009.02330.x"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fepi.13411","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.13411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T13:20:07Z","timestamp":1696339207000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.13411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,24]]},"references-count":9,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1111\/epi.13411"],"URL":"https:\/\/doi.org\/10.1111\/epi.13411","archive":["Portico"],"relation":{},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,24]]}}}