{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T20:03:01Z","timestamp":1760299381479},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T00:00:00Z","timestamp":1466985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001824","name":"Grantov\u00e1 Agentura \u010cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["P304\/12\/G069","P302\/10\/0971","15\u201016605S"],"award-info":[{"award-number":["P304\/12\/G069","P302\/10\/0971","15\u201016605S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2016,8]]},"abstract":"Summary<\/jats:title>Possible changes of cortical excitability after status epilepticus (SE<\/jats:styled-content>) elicited in 12\u2010day\u2010old rats were studied by means of paired cortical afterdischarges (AD<\/jats:styled-content>s). Consequences of lithium\u2010pilocarpine status were studied in animals with implanted electrodes 3, 6, 9, 13, and 26 days after SE<\/jats:styled-content>. Paired low\u2010frequency stimulation with a 1\u2010min interval was repeated after 10 min, and duration of AD<\/jats:styled-content>s was measured. Control rats received saline instead of pilocarpine; other treatments were the same as in SE<\/jats:styled-content> group. Postictal refractoriness (i.e., the testing response significantly shorter than the conditioning one) appeared at the age of 18 days in lithium\u2010paraldehyde controls, whereas SE<\/jats:styled-content> animals exhibited this phenomenon since postnatal day 21. The only significant difference between SE<\/jats:styled-content> and lithium\u2010paraldehyde controls was found in the second conditioning AD<\/jats:styled-content> in the oldest group studied\u2013it was longer in 38\u2010day\u2010old SE<\/jats:styled-content> animals. Our results demonstrated moderate signs of higher excitability of SE<\/jats:styled-content> rats in comparison with control ones long before appearance of spontaneous seizures.<\/jats:p>","DOI":"10.1111\/epi.13438","type":"journal-article","created":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T10:42:59Z","timestamp":1467024179000},"source":"Crossref","is-referenced-by-count":4,"title":["Does status epilepticus induced at early postnatal period change excitability after cortical epileptic afterdischarges?"],"prefix":"10.1111","volume":"57","author":[{"given":"Pavel","family":"Mare\u0161","sequence":"first","affiliation":[{"name":"Department of Developmental Epileptology Institute of Physiology Czech Academy of Sciences Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Kubov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Developmental Epileptology Institute of Physiology Czech Academy of Sciences Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2012.12.055"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0001-37652009000300003"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00680.2005"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/157015908783769653"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-017-8914-1_11"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2005.00301.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2013.00142"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1995.tb00954.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12870"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410130514"},{"issue":"20","key":"e_1_2_7_12_1","first-page":"183","article-title":"Increased epileptogenesis in the immature hippocampus","author":"Vel\u00ed\u0161ek L","year":"1991","journal-title":"Exp Brain Res"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(72)90177-0"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-1211(02)00009-8"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2014.09.007"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1996.76.2.1282"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2009.02094.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410320504"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fepi.13438","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.13438","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T13:01:55Z","timestamp":1694955715000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.13438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,27]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1111\/epi.13438"],"URL":"https:\/\/doi.org\/10.1111\/epi.13438","archive":["Portico"],"relation":{},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,27]]}}}