{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T22:25:04Z","timestamp":1783031104229,"version":"3.54.6"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T00:00:00Z","timestamp":1479254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Vestre Viken Hospital Trust"},{"name":"The Norwegian Epilepsy Association"},{"name":"Lied, Nicolaysen and R\u00f8mcke's Memorial Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Despite juvenile myoclonic epilepsy (<jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content>) being considered one of the most common epilepsies, population\u2010based prevalence studies of <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content> are lacking. Our aim was to estimate the prevalence of <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content> in a Norwegian county, using updated diagnostic criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a cross\u2010sectional study, based on reviews of the medical records of all patients with a diagnosis of epilepsy at Drammen Hospital in the period 1999\u20132013. The study population consisted of 98,152 people &lt;30 years of age. Subjects diagnosed with <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content>, unspecified genetic generalized epilepsy, or absence epilepsy were identified. All of these patients were contacted and asked specifically about myoclonic jerks. Electroencephalography (<jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>) recordings and medical records were reevaluated for those who confirmed myoclonic jerks. Information about seizure onset was obtained from the medical records, and annual frequency of new cases was estimated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 55 subjects fulfilled the diagnostic criteria for <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content>. The point prevalence was estimated at 5.6\/10,000. <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content> constituted 9.3% of all epilepsies in the age group we investigated. Of subjects diagnosed with either unspecified genetic generalized epilepsy or absence epilepsy, 21% and 12%, respectively, had <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content>. We identified 21 subjects with <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content> (38%) who had not been diagnosed previously. Six subjects (11%) had childhood absence epilepsy evolving into <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content>. Between 2009 and 2013, the average frequency of <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content> per 100,000 people of all ages per year was estimated at 1.7.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>A substantial portion of people with <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content> seem to go undiagnosed, as was the case for more than one third of the subjects in this study. By investigating subjects diagnosed with unspecified genetic generalized epilepsy or absence epilepsy, we found a prevalence of <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content> that was considerably higher than previously reported. We conclude that <jats:styled-content style=\"fixed-case\">JME<\/jats:styled-content> may go undiagnosed due to the underrecognition of myoclonic jerks. To make a correct diagnosis, clinicians need to ask specifically about myoclonic jerks.<\/jats:p><\/jats:sec>","DOI":"10.1111\/epi.13613","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T20:01:18Z","timestamp":1479326478000},"page":"105-112","source":"Crossref","is-referenced-by-count":43,"title":["Prevalence of juvenile myoclonic epilepsy in people &lt;30 years of age\u2014A population\u2010based study in Norway"],"prefix":"10.1111","volume":"58","author":[{"given":"Marte","family":"Syvertsen","sequence":"first","affiliation":[{"name":"Department of Neurology Drammen Hospital Vestre Viken Hospital Trust Drammen Norway"},{"name":"Institute of Clinical Medicine University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten Kristoffer","family":"Hellum","sequence":"additional","affiliation":[{"name":"Department of Neurology Drammen Hospital Vestre Viken Hospital Trust Drammen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnar","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Neurology Drammen Hospital Vestre Viken Hospital Trust Drammen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Edland","sequence":"additional","affiliation":[{"name":"Department of Neurology Drammen Hospital Vestre Viken Hospital Trust Drammen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl Otto","family":"Nakken","sequence":"additional","affiliation":[{"name":"Division of Clinical Neuroscience National Center for Epilepsy Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaja Kristine","family":"Selmer","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Oslo University Hospital and University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette","family":"Koht","sequence":"additional","affiliation":[{"name":"Department of Neurology Drammen Hospital Vestre Viken Hospital Trust Drammen Norway"},{"name":"Institute of Clinical Medicine University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2002.04602.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00242439"},{"key":"e_1_2_8_4_1","first-page":"2415","article-title":"En kontrolleret social og psychologisk unders\u00f8gelse af patienter med juvenil myoklon epilepsi [A controlled social and psychological investigation of patients with juvenile myoclonic epilepsy]","volume":"137","author":"Lund M","year":"1975","journal-title":"Ugeskr Laeger"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2012.10.034"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2012.06.024"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2005.00309.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.2000.tb00246.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12972"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1986.tb04642.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1983.tb04893.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1999.tb02036.x"},{"key":"e_1_2_8_13_1","first-page":"63","article-title":"A clinical and epidemiological study of adult patients with epilepsy","volume":"94","author":"Wagner AL","year":"1983","journal-title":"Acta Neurol Scand Suppl"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1991.tb04708.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2016.01.015"},{"key":"e_1_2_8_16_1","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1001\/archneur.58.9.1487","article-title":"Juvenile myoclonic epilepsy","volume":"58","author":"Genton P","year":"2001","journal-title":"Arch Neurol"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2012.11.051"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_8_19_1","unstructured":"Statistics Norway.Table 07459: population by sex and one\u2010year age groups. 1 January (M). 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