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Articles investigating the epidemiology of epilepsy, diagnosis, comorbidities and associated mortality, stigmatization, and treatment were included. Epilepsy is a global health care issue affecting up to 70 million people worldwide. Nearly 80% of people with epilepsy live in low\u2010 and middle\u2010income countries with limited resources. People with epilepsy are prone to physical and psychological comorbidities, including anxiety and depression, which can negatively impact their quality of life. Furthermore, people with epilepsy are at higher risk of premature death than people without epilepsy. Discrimination or stigmatization of people with epilepsy is common in Asia and can affect their education, work, and marriage opportunities. Access to epilepsy treatment varies throughout Asia. Although highly advanced treatment is available in some countries, up to 90% of people with epilepsy are not adequately treated or are not treated with conventional antiepileptic therapy in resource\u2010limited countries. People in remote areas often do not receive any epilepsy care. First\u2010generation antiepileptic drugs (\n                    <jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>\n                    s) are available, but usually only in urban areas, and second\u2010generation\n                    <jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>\n                    s are not available in all countries. Newer\n                    <jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>\n                    s tend to have more favorable safety profiles than first\u2010generation\n                    <jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>\n                    s and provide options to tailor therapy for individual patients, especially those with comorbidities. Active epilepsy surgery centers are present in some countries, although epilepsy surgery is often underutilized given the number of patients who could benefit. Further epidemiologic research is needed to provide accurate epilepsy data across the Asian region. Coordinated action is warranted to improve access to treatment and care.\n                  <\/jats:p>","DOI":"10.1111\/epi.14458","type":"journal-article","created":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T16:30:17Z","timestamp":1530203417000},"page":"7-21","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":206,"title":["Epilepsy in Asia: Disease burden, management barriers, and challenges"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5950-2692","authenticated-orcid":false,"given":"Eugen","family":"Trinka","sequence":"first","affiliation":[{"name":"Department of Neurology Christian Doppler Klinik University Hospital Paracelsus Medical University Salzburg Austria"},{"name":"Institute of Public Health Medical Decision Making, and Health Technology Assessment University for Health Sciences, Medical Informatics, and Technology Hall in Tyrol Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Kwan","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Neurology University of Melbourne Royal Melbourne Hospital Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ByungIn","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology Inje University School of Medicine Haeundae Paik Hospital Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amitabh","family":"Dash","sequence":"additional","affiliation":[{"name":"Eisai Singapore Pte Ltd Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,6,28]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"World Health Organization.Epilepsy. 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