{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T16:12:59Z","timestamp":1785946379793,"version":"3.56.0"},"reference-count":14,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T00:00:00Z","timestamp":1535932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    The magnitude of the treatment gap (\n                    <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>\n                    ) for convulsive status epilepticus (\n                    <jats:styled-content style=\"fixed-case\">CSE<\/jats:styled-content>\n                    ) in resource\u2010poor countries is unknown. Hospital\u2010based cohort studies from developing countries revealed that the management of\n                    <jats:styled-content style=\"fixed-case\">CSE<\/jats:styled-content>\n                    was usually suboptimal due to lack of advanced diagnostic and treatment facilities, significant delay in patient's presentation at hospital, and shortages of essential antiepileptic drugs (\n                    <jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>\n                    s). However, there were no significant differences in the proportion of refractory status epilepticus, short\u2010term mortalities, and morbidities of\n                    <jats:styled-content style=\"fixed-case\">CSE<\/jats:styled-content>\n                    between the developed and the developing countries. Therefore, the presence of significant\n                    <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>\n                    for\n                    <jats:styled-content style=\"fixed-case\">CSE<\/jats:styled-content>\n                    in developing countries is still an assumption without evidence. We conducted an expert survey in Asia for potential sources of\n                    <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>\n                    . Experts from 16 Asian countries responded to the questionnaire. An injectable form of diazepam was available in all 16 countries even at the primary care level, but intravenous lorazepam was available only in four countries. Second\u2010line\n                    <jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>\n                    s were widely available at tertiary care hospitals, but not at primary care hospitals. Lack of second\u2010line\n                    <jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>\n                    s at primary care hospitals, significant delay in patient transportation to the hospital, shortages of intensive care unit facilities, and absence of trained physicians were important contributing factors to\n                    <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>\n                    in Asia.\n                  <\/jats:p>","DOI":"10.1111\/epi.14484","type":"journal-article","created":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T03:55:03Z","timestamp":1535946903000},"page":"135-139","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Treatment gap for convulsive status epilepticus in resource\u2010poor countries"],"prefix":"10.1111","volume":"59","author":[{"given":"Byungin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Neurology Epilepsy Center Inje University School of Medicine Haeundae Paik Hospital Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Asian Status Epilepticus Survey Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,9,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2010.09.003"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70331-9"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2015.04.040"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.43.s.6.13.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.43.s.6.4.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01693.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.09.064147"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01556.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01214.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2016.0832"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2015.0753"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2010.05.007"},{"key":"e_1_2_7_14_1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1684\/epd.2013.0604","article-title":"Adult tonic\u2010clonic convulsive status epilepticus over the last 11\u00a0years in a resource\u2010poor country: a tertiary referral centre study from southern Thailand","volume":"15","author":"Phabphal K","year":"2013","journal-title":"Epileptic Disord"},{"key":"e_1_2_7_15_1","first-page":"271","article-title":"Is the Thailand epilepsy service adequate to help patients?","volume":"18","author":"Tiamkao S","year":"2013","journal-title":"Neurology Asia"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fepi.14484","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.14484","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T14:47:15Z","timestamp":1694875635000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.14484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,3]]},"references-count":14,"journal-issue":{"issue":"S2","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1111\/epi.14484"],"URL":"https:\/\/doi.org\/10.1111\/epi.14484","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.733939146.793551336","asserted-by":"object"}]},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,3]]},"assertion":[{"value":"2017-10-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}