{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:49:28Z","timestamp":1787014168932,"version":"build-2736575974"},"reference-count":12,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,7,15]],"date-time":"2018-07-15T00:00:00Z","timestamp":1531612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000156","name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"publisher","award":["28178"],"award-info":[{"award-number":["28178"]}],"id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000095","name":"Savoy Foundation","doi-asserted-by":"publisher","award":["2017\u20102018"],"award-info":[{"award-number":["2017\u20102018"]}],"id":[{"id":"10.13039\/501100000095","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Sleep\u2010related hypermotor epilepsy (\n                    <jats:styled-content style=\"fixed-case\">SHE<\/jats:styled-content>\n                    ) is an epilepsy syndrome that is characterized by the occurrence of sleep\u2010related hypermotor seizures of variable complexity and duration. Seizures usually arise in the frontal lobe, but extrafrontal seizure onset zones are well described. To identify clinically relevant ictal features of\n                    <jats:styled-content style=\"fixed-case\">SHE<\/jats:styled-content>\n                    that could distinguish a frontal from an extrafrontal onset zone, we conducted a retrospective analysis of seizure characteristics in 58 patients with drug\u2010resistant\n                    <jats:styled-content style=\"fixed-case\">SHE<\/jats:styled-content>\n                    (43 frontal and 15 extrafrontal) who underwent video\u2010stereo\u2010electroencephalographic recordings and became seizure\u2010free after epilepsy surgery. We found that the mean duration of electrographic seizures and clinically observable ictal manifestations were significantly shorter in frontal\n                    <jats:styled-content style=\"fixed-case\">SHE<\/jats:styled-content>\n                    compared to extrafrontal\n                    <jats:styled-content style=\"fixed-case\">SHE<\/jats:styled-content>\n                    . The mean latency between electrographic seizure onset and the onset of hypermotor manifestations was also shorter in frontal\n                    <jats:styled-content style=\"fixed-case\">SHE<\/jats:styled-content>\n                    . Accordingly, a latency &gt; 5\u00a0seconds between the first video\u2010detectable movement (eg, eye opening or a minor motor event) and the onset of hypermotor manifestations yielded a sensitivity of 75% and a specificity of 90% for an extrafrontal onset, thereby indicating that specific ictal features in\n                    <jats:styled-content style=\"fixed-case\">SHE<\/jats:styled-content>\n                    can provide clinically useful clues to increase diagnostic accuracy in this syndrome.\n                  <\/jats:p>","DOI":"10.1111\/epi.14517","type":"journal-article","created":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T02:24:12Z","timestamp":1531707852000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Seizure duration and latency of hypermotor manifestations distinguish frontal from extrafrontal onset in sleep\u2010related hypermotor epilepsy"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8489-4907","authenticated-orcid":false,"given":"Steve A.","family":"Gibbs","sequence":"first","affiliation":[{"name":"Department of Neurosciences Center of Sleep Medicine, C. Munari Center for Epilepsy Surgery Hospital Niguarda Milan Italy"},{"name":"Department of Neurosciences Center for Advanced Research in Sleep Medicine Sacred Heart Hospital of Montreal University of Montreal Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Proserpio","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Center of Sleep Medicine, C. Munari Center for Epilepsy Surgery Hospital Niguarda Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Francione","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Center of Sleep Medicine, C. Munari Center for Epilepsy Surgery Hospital Niguarda Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Mai","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Center of Sleep Medicine, C. Munari Center for Epilepsy Surgery Hospital Niguarda Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Cossu","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Center of Sleep Medicine, C. Munari Center for Epilepsy Surgery Hospital Niguarda Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Tassi","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Center of Sleep Medicine, C. Munari Center for Epilepsy Surgery Hospital Niguarda Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lino","family":"Nobili","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Center of Sleep Medicine, C. Munari Center for Epilepsy Surgery Hospital Niguarda Milan Italy"},{"name":"Unit of Child Neuropsychiatry Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI)\u2010Department of Neurosciences Giannina Gaslini Institute University of Genoa Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002666"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.05.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000106945.68292.DC"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2006.00510.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03254.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e31827d1161"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12490"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2011.10.018"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-005-0492-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2009.02169.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001591"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003459"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fepi.14517","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.14517","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T04:43:15Z","timestamp":1694752995000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.14517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,15]]},"references-count":12,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1111\/epi.14517"],"URL":"https:\/\/doi.org\/10.1111\/epi.14517","archive":["Portico"],"relation":{},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,15]]},"assertion":[{"value":"2018-01-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}