{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T15:51:49Z","timestamp":1770738709611,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T00:00:00Z","timestamp":1580947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007321","name":"Finding A Cure for Epilepsy and Seizures","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007321","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Excess mortality due to epilepsy is greatest among young adults. However, the relative proportions of sudden unexpected death in epilepsy (SUDEP) and other epilepsy\u2010related causes of death are not well defined. We prospectively adjudicated cause of death in all 18\u2010 to 45\u2010year\u2010olds with a history of seizure\/epilepsy who underwent medicolegal investigation in San Diego County between 2014 and 2017. We identified 108 decedents with definite or probable epilepsy; 62% died from an epilepsy\u2010related cause. SUDEP accounted for 42.6% (N\u00a0=\u00a046) of deaths, which were usually unwitnessed deaths, at home in bed. Other frequent causes of death were drug overdose (N\u00a0=\u00a023), suicide (N\u00a0=\u00a08), trauma (N\u00a0=\u00a08), and drowning (N\u00a0=\u00a06). SUDEP autopsies were similar to those of decedents from other causes. Most deaths in young adults with epilepsy that undergo medico\u2010legal investigation are epilepsy\u2010related, and SUDEP is the leading cause. Improved seizure control can potentially save many lives.<\/jats:p>","DOI":"10.1111\/epi.16443","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T05:50:56Z","timestamp":1581054656000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["SUDEP among young adults in the San Diego County Medical Examiner Office"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1030-2101","authenticated-orcid":false,"given":"Esma","family":"Karlovich","sequence":"first","affiliation":[{"name":"Department of Neurology Comprehensive Epilepsy Center NYU Langone Health New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0044-4632","authenticated-orcid":false,"given":"Orrin","family":"Devinsky","sequence":"additional","affiliation":[{"name":"Department of Neurology Comprehensive Epilepsy Center NYU Langone Health New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Brandsoy","sequence":"additional","affiliation":[{"name":"San Diego County Medical Examiner's Office San Diego CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1068-1797","authenticated-orcid":false,"given":"Daniel","family":"Friedman","sequence":"additional","affiliation":[{"name":"Department of Neurology Comprehensive Epilepsy Center NYU Langone Health New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13604"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002253"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12666"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0911610"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003685"},{"key":"e_1_2_7_7_1","unstructured":"Centersfor Disease Control and Prevention.Center for State Tribal Local and Territorial Support Public Health Law Program. Investigations and Autopsies: updated 2015.https:\/\/www.cdc.gov\/phlp\/publications\/coroner\/investigations.html. Accessed August 1 2019."},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03121.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.14195"},{"key":"e_1_2_7_10_1","unstructured":"United States Census Bureau.American FactFinder.https:\/\/factfinder.census.gov\/faces\/nav\/jsf\/pages\/index.xhtml. Accessed November 1 2019."},{"key":"e_1_2_7_11_1","unstructured":"Centersfor Disease Control and Prevention.National Center for Health Statistics. National Health Interview Survey.https:\/\/www.cdc.gov\/nchs\/nhis\/index.htm. Accessed November 1 2019."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(16)30158-2"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.14079"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000323813.36193.4d"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005035"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2003.08.019"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2014.06.021"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2003.10.002"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60899-5"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fepi.16443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.16443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/epi.16443","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.16443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T20:34:06Z","timestamp":1694032446000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.16443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,6]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1111\/epi.16443"],"URL":"https:\/\/doi.org\/10.1111\/epi.16443","archive":["Portico"],"relation":{},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,6]]},"assertion":[{"value":"2019-08-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}