{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T01:51:38Z","timestamp":1777686698874,"version":"3.51.4"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:00:00Z","timestamp":1689292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The present study was aimed at investigating the effects of anti\u2010seizure medications (ASMs), patient demographic characteristics, and the seizure type and frequency on the development of congenital malformations (CMs) in the infants of pregnant women with epilepsy (PWWE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>PWWE followed up at the neurology outpatient clinic of 21 centers between 2014 and 2019 were included in this prospective study. The follow\u2010up of PWWE was conducted using structured, general pregnant follow\u2010up forms prepared by the Pregnancy and Epilepsy Study Committee. The newborns were examined by a neonatologist after delivery and at 1 and 3 months postpartum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the infants of 759 PWWE, 7.2% had CMs, with 5.6% having major CMs. Polytherapy, monotherapy, and no medications were received by 168 (22.1%), 548 (72.2 %), and 43 (5.7 %) patients, respectively. CMs were detected at an incidence of 2.3% in infants of PWWE who did not receive medication, 5.7% in infants of PWWE who received monotherapy, and 13.7% in infants of PWWE who received polytherapy. The risk of malformation was 2.31\u2010fold (95% confidence interval (CI): 1.48\u20134.61, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) higher in infants of PWWE who received polytherapy. Levetiracetam was the most frequently used seizure medication as monotherapy, with the highest incidence of CMs occurring with valproic acid (VPA) use (8.5%) and the lowest with lamotrigine use (2.1%). The incidence of CMs was 5% at a carbamazepine dose &lt;700\u2009mg, 10% at a carbamazepine dose \u2265700\u2009mg, 5.5% at a VPA dose &lt;750\u2009mg, and 14.8% at a VPA dose \u2265750\u2009mg. Thus the risk of malformation increased 2.33 times (<jats:italic>p<\/jats:italic>\u2009=\u2009.041) in infants of PWWE receiving high\u2010dose ASMs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>Birth outcomes of PWWE receiving and not receiving ASMs were evaluated. The risk of CMs occurrence was higher, particularly in infants of PWWE using VPA and receiving polytherapy. The incidence of CMs was found to be lower in infants of PWWE receiving lamotrigine.<\/jats:p><\/jats:sec>","DOI":"10.1111\/epi.17692","type":"journal-article","created":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T05:04:31Z","timestamp":1687755871000},"page":"2310-2321","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Birth outcomes in pregnant women with epilepsy: A Nationwide multicenter study from T\u00fcrkiye"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9126-9192","authenticated-orcid":false,"given":"Mehmet Taylan","family":"Pekoz","sequence":"first","affiliation":[{"name":"Department of Neurology \u00c7ukurova University School of Medicine  Adana T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3868-9814","authenticated-orcid":false,"given":"Kezban","family":"Aslan\u2010Kara","sequence":"additional","affiliation":[{"name":"Department of Neurology \u00c7ukurova University School of Medicine  Adana T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8946-6952","authenticated-orcid":false,"given":"Bet\u00fcl","family":"Tekin","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Bak\u0131rkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Diseases Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3752-1825","authenticated-orcid":false,"given":"Candan","family":"Gurses","sequence":"additional","affiliation":[{"name":"Department of Neurology Ko\u00e7 University School of Medicine  \u0130stanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7372-5430","authenticated-orcid":false,"given":"Seher Naz","family":"Yeni","sequence":"additional","affiliation":[{"name":"Department of Neurology Istanbul University\u2013Cerrahpasa School of Medicine  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8402-4277","authenticated-orcid":false,"given":"Hacer","family":"Bozdemir","sequence":"additional","affiliation":[{"name":"Department of Neurology \u00c7ukurova University School of Medicine  Adana T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1976-7319","authenticated-orcid":false,"given":"Selda","family":"Keskin\u2010Guler","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Ankara Training and Research Hospital  Ankara T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6458-8374","authenticated-orcid":false,"given":"Dilek","family":"Atakl\u0131","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Bak\u0131rkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Diseases Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2485-1654","authenticated-orcid":false,"given":"Gunay","family":"Gul","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Bak\u0131rkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Diseases Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9787-7551","authenticated-orcid":false,"given":"Fulya","family":"Eren","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Bak\u0131rkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Diseases Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2787-1303","authenticated-orcid":false,"given":"H\u00fcseyin","family":"Sar\u0131","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Bak\u0131rkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Diseases Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3256-5394","authenticated-orcid":false,"given":"Zeynep Ba\u015ftug","family":"Gul","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Bak\u0131rkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Diseases Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8658-1568","authenticated-orcid":false,"given":"Ayten","family":"Ceyhan\u2010Dirican","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Bak\u0131rkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Diseases Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6062-3694","authenticated-orcid":false,"given":"Fatma","family":"Genc","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Antalya Training and Research Hospital  Antalya T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5043-0891","authenticated-orcid":false,"given":"Yasemin","family":"Bicer\u2010Gomceli","sequence":"additional","affiliation":[{"name":"Department of Neurology Antalya Training and Research Hospital  Antalya T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0548-1838","authenticated-orcid":false,"given":"Cigdem","family":"Ozkara","sequence":"additional","affiliation":[{"name":"Department of Neurology Istanbul University\u2013Cerrahpasa School of Medicine  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5011-8929","authenticated-orcid":false,"given":"Sakir","family":"Delil","sequence":"additional","affiliation":[{"name":"Department of Neurology Istanbul University\u2013Cerrahpasa School of Medicine  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0328-9607","authenticated-orcid":false,"given":"Arife Cimen","family":"Atalar","sequence":"additional","affiliation":[{"name":"Department of Neurology Istanbul University School of Medicine  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4749-1471","authenticated-orcid":false,"given":"Nerses","family":"Bebek","sequence":"additional","affiliation":[{"name":"Department of Neurology Istanbul University School of Medicine  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3360-659X","authenticated-orcid":false,"given":"Bet\u00fcl","family":"Baykan","sequence":"additional","affiliation":[{"name":"Department of Neurology Istanbul University School of Medicine  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9435-6037","authenticated-orcid":false,"given":"\u0130brahim","family":"Bora","sequence":"additional","affiliation":[{"name":"Department of Neurology Uludag University School of Medicine  Bursa T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6739-8605","authenticated-orcid":false,"given":"Aylin","family":"Bican\u2010Demir","sequence":"additional","affiliation":[{"name":"Department of Neurology Uludag University School of Medicine  Bursa T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3694-1596","authenticated-orcid":false,"given":"Cemile Handan","family":"M\u0131s\u0131rl\u0131","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Haydarpasa Numune Training and Research Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0986-3924","authenticated-orcid":false,"given":"Kemal","family":"Tutkavul","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Haydarpasa Numune Training and Research Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0352-702X","authenticated-orcid":false,"given":"Sibel K.","family":"Velioglu","sequence":"additional","affiliation":[{"name":"Department of Neurology Karadeniz Technical University School of Medicine  Trabzon T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3322-5105","authenticated-orcid":false,"given":"Demet","family":"Ilhan\u2010Algin","sequence":"additional","affiliation":[{"name":"Department of Neurology Osmangazi University School of Medicine  Eskisehir T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2149-392X","authenticated-orcid":false,"given":"Oguz","family":"Erdinc","sequence":"additional","affiliation":[{"name":"Department of Neurology Osmangazi University School of Medicine  Eskisehir T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7329-7138","authenticated-orcid":false,"given":"Serap","family":"Saygi","sequence":"additional","affiliation":[{"name":"Department of Neurology Hacettepe University School of Medicine  Ankara T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8575-9574","authenticated-orcid":false,"given":"Irsel","family":"Tezer\u2010F\u0131l\u0131k","sequence":"additional","affiliation":[{"name":"Department of Neurology Hacettepe University School of Medicine  Ankara T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6818-3021","authenticated-orcid":false,"given":"Ebru","family":"Apayd\u0131n\u2010Dogan","sequence":"additional","affiliation":[{"name":"Department of Neurology Akdeniz University School of Medicine  Antalya T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4053-2928","authenticated-orcid":false,"given":"Ali","family":"Akyol","sequence":"additional","affiliation":[{"name":"Department of Neurology Adnan Menderes University School of Medicine  Ayd\u0131n T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1114-7860","authenticated-orcid":false,"given":"Ozden","family":"Kamisli","sequence":"additional","affiliation":[{"name":"Department of Neurology \u0130n\u00f6n\u00fc University Turgut \u00d6zal Medical Center Training and Research Hospital  Malatya T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4719-5741","authenticated-orcid":false,"given":"A. Destina","family":"Yalc\u0131n","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Umraniye Training and Research Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5954-6484","authenticated-orcid":false,"given":"Gonul","family":"Cakmak","sequence":"additional","affiliation":[{"name":"Department of Neurology Sanko University Faculty of Medicine  Gaz\u0131antep T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4968-0786","authenticated-orcid":false,"given":"Alevtina","family":"Ersoy","sequence":"additional","affiliation":[{"name":"Department of Neurology Erzincan Binali Yildirim University School of Medicine  Erzincan T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1165-2648","authenticated-orcid":false,"given":"Sibel","family":"Ustun\u2010Ozek","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Prof. Dr. Cemil Ta\u015f\u00e7\u0131o\u011flu City Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3551-1604","authenticated-orcid":false,"given":"Gulistan","family":"Halac","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Bezm\u2010i Alem Valide Sultan Vakif Gureba Training and Research Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9325-4151","authenticated-orcid":false,"given":"Gulnihal","family":"Kutlu","sequence":"additional","affiliation":[{"name":"Department of Neurology Mugla S\u0131tk\u0131 Kocman University School of Medicine  Mu\u011fla T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7414-3800","authenticated-orcid":false,"given":"Aygul","family":"Tantik\u2010Pak","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Health Sciences, Gaziosmanpasa Training and Research Hospital  Istanbul T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5768-3549","authenticated-orcid":false,"given":"Sevinc P.","family":"Y\u00fccel","sequence":"additional","affiliation":[{"name":"Department of Biostatistics \u00c7ukurova University School of Medicine  Adana T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2018.1550073"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2018.11.010"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.21763\/tjfmpc.296272"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000006173"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30107-8"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharep.2019.01.011"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-013-7239-x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2013-306318"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.2270"},{"key":"e_1_2_8_11_1","first-page":"21","article-title":"Prenatal exposure to Valproic acid affects microglia and synaptic ultrastructure in a brain\u2010region\u2010specific manner in young\u2010adult male rats: relevance to autism Spectrum disorders","volume":"18","author":"Gassowska\u2010Dobrowolska M","year":"2020","journal-title":"Int J Mol Sci"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871527320666210806165430"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2020.05.011"},{"issue":"7","key":"e_1_2_8_14_1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-017248","article-title":"Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta\u2010analysis","volume":"20","author":"Veroniki AA","year":"2017","journal-title":"BMJ Open"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182a43e81"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70107-7"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2008.156109"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2015.02.019"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13632"},{"key":"e_1_2_8_20_1","first-page":"60","article-title":"Pregnancy in women with epilepsy: preliminary results of Kerala registry of epilepsy and pregnancy","volume":"49","author":"Thomas SV","year":"2001","journal-title":"Neurol India"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.17712\/nsj.2020.1.20190077"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmw019"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2019.106250"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.14086"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13671"},{"key":"e_1_2_8_26_1","volume-title":"EUROCAT European surveillance of congenital anomalies. Guide 1.3","author":"EUROCAT"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j2249"},{"key":"e_1_2_8_28_1","article-title":"Congenital anomalies in Rio Grande do Sul state: a time series analysis rev bras","volume":"22","author":"Luz GDS","year":"2019","journal-title":"Epidemiology"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.2188\/jea.JE20160108"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/920940"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(96)02743-9"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30281-3"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2004.451101.x"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000163771.96962.1F"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2012.03625.x"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12001"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2017.03.026"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182574f39"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70103-5"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2018.12.006"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19138079"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta4160"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/epi.17692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T19:54:03Z","timestamp":1700682843000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.17692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,14]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1111\/epi.17692"],"URL":"https:\/\/doi.org\/10.1111\/epi.17692","archive":["Portico"],"relation":{},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,14]]},"assertion":[{"value":"2022-09-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}