{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:17:20Z","timestamp":1775002640568,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,6]],"date-time":"2023-07-06T00:00:00Z","timestamp":1688601600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR001873"],"award-info":[{"award-number":["UL1TR001873"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000051","name":"National Human Genome Research Institute","doi-asserted-by":"publisher","award":["RM1HG007257"],"award-info":[{"award-number":["RM1HG007257"]}],"id":[{"id":"10.13039\/100000051","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS104076"],"award-info":[{"award-number":["R01NS104076"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Hispanics continue to face challenges when trying to access health care, including epilepsy care and genetic\u2010related health care services. This study examined epilepsy genetic knowledge and beliefs in this historically underserved population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Questionnaires were completed by 641 adults with epilepsy without identified cause, of whom 122 self\u2010identified as Hispanic or Latino and 519 as non\u2010Hispanic. Participants were asked about their views on the contribution of genetics to the cause of their epilepsy (\u201cgenetic attribution\u201d), optimism for advancements in epilepsy genetic research (\u201cgenetic optimism\u201d), basic genetic knowledge, and epilepsy\u2010specific genetic knowledge. Generalized linear models were used to compare the two groups in the means of quantitative measures and percents answered correctly for individual genetic knowledge items. Analyses were adjusted for age, sex, education, religion, family history of epilepsy, and time since last seizure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Hispanics did not differ from non\u2010Hispanics in genetic attribution, genetic optimism, or number of six basic genetic knowledge items answered correctly. The number of nine epilepsy\u2010specific genetic knowledge items answered correctly was significantly lower for Hispanics than non\u2010Hispanics (adjusted mean\u2009=\u20096.0 vs. 6.7, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). After adjustment for education and other potential mediators, the proportion answered correctly was significantly lower for Hispanics than non\u2010Hispanics for only two items related to family history and penetrance of epilepsy\u2010related genes. Only 54% of Hispanics and 61% of non\u2010Hispanics answered correctly that \u201cIf a person has epilepsy, his or her relatives have an increased chance of getting epilepsy.\u201d<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>Despite large differences in sociodemographic variables including education, most attitudes and beliefs about genetics were similar in Hispanics and non\u2010Hispanics. Epilepsy\u2010specific genetic knowledge was lower among Hispanics than non\u2010Hispanics, and this difference was mostly mediated by differences in demographic variables. Genetic counseling should address key concepts related to epilepsy genetics to ensure they are well understood by both Hispanic and non\u2010Hispanic patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/epi.17701","type":"journal-article","created":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T01:34:51Z","timestamp":1687656891000},"page":"2443-2453","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Knowledge and beliefs about epilepsy genetics among Hispanic and <scp>non\u2010Hispanic<\/scp> patients"],"prefix":"10.1111","volume":"64","author":[{"given":"Shannon","family":"Trujillo","sequence":"first","affiliation":[{"name":"Division of Maternal\u2013Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences Rutgers Robert Wood Johnson Medical School  New Brunswick New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Wetmore","sequence":"additional","affiliation":[{"name":"Gertrude H. Sergievsky Center Columbia University Irving Medical Center  New York New York USA"},{"name":"Department of Epidemiology Columbia University Mailman School of Public Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itzel A.","family":"Camarillo","sequence":"additional","affiliation":[{"name":"Gertrude H. Sergievsky Center Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylwia","family":"Misiewicz","sequence":"additional","affiliation":[{"name":"Gertrude H. Sergievsky Center Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halie","family":"May","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"},{"name":"Institute for Genomic Medicine Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0826-2350","authenticated-orcid":false,"given":"Hyunmi","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Neurology Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karolynn","family":"Siegel","sequence":"additional","affiliation":[{"name":"Department of Sociomedical Sciences Columbia University Mailman School of Public Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy K.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"},{"name":"Department of Pediatrics Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo C.","family":"Phelan","sequence":"additional","affiliation":[{"name":"Department of Sociomedical Sciences Columbia University Mailman School of Public Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence H.","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Columbia University Mailman School of Public Health  New York New York USA"},{"name":"School of Global Public Health New York University  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng\u2010Shiun","family":"Leu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Columbia University Mailman School of Public Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda L.","family":"Bergner","sequence":"additional","affiliation":[{"name":"Department of Genetics and Development Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"},{"name":"Genetic Counseling Graduate Program Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7074-242X","authenticated-orcid":false,"given":"Ruth","family":"Ottman","sequence":"additional","affiliation":[{"name":"Gertrude H. 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