{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:21:46Z","timestamp":1792596106595,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T00:00:00Z","timestamp":1698192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This longitudinal cohort study aimed to identify trajectories of parent well\u2010being over the first 2\u2009years after their child's evaluation for candidacy for epilepsy surgery, and to identify the baseline clinical and demographic characteristics associated with these trajectories. Parent well\u2010being was based on parent depressive and anxiety symptoms and family resources (i.e., family mastery and social support).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Parents of 259 children with drug\u2010resistant epilepsy (105 of whom eventually had surgery) were recruited from eight epilepsy centers across Canada at the time of their evaluation for epilepsy surgery candidacy. Participants were assessed at baseline and 6\u2010month, 1\u2010year, and 2\u2010year follow\u2010up. The trajectories of parents' depressive symptoms, anxiety symptoms, and family resources were jointly estimated using multigroup latent class growth models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analyses identified three trajectories: an optimal\u2010stable group with no\/minimal depressive or anxiety symptoms, and high family resources that remained stable over time; a mild\u2010decreasing\u2010plateau group with mild depressive and anxiety symptoms that decreased over time then plateaued, and intermediate family resources that remained stable; and a moderate\u2010decreasing group with moderate depressive and anxiety symptoms that decreased slightly, and low family resources that remained stable over time. Parents of children with higher health\u2010related quality of life, fathers, and parents who had higher household income were more likely to have better trajectories of well\u2010being. Treatment type was not associated with the trajectory groups, but parents whose children were seizure\u2010free at the time of the last follow\u2010up were more likely to have better trajectories (optimal\u2010stable or mild\u2010decreasing\u2010plateau trajectories).<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>This study documented distinct trajectories of parent well\u2010being, from the time of the child's evaluation for epilepsy surgery. Parents who present with anxiety and depressive symptoms and low family resources do not do well over time. They should be identified and offered supportive services early in their child's epilepsy treatment history.<\/jats:p><\/jats:sec>","DOI":"10.1111\/epi.17797","type":"journal-article","created":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T05:23:50Z","timestamp":1697174630000},"page":"3342-3353","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Trajectories of parent well\u2010being in children with drug\u2010resistant epilepsy"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1937-1026","authenticated-orcid":false,"given":"Mary Lou","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Psychology University of Toronto Mississauga  Mississauga Ontario Canada"},{"name":"Neurosciences and Mental Health Program Hospital for Sick Children  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7763-988X","authenticated-orcid":false,"given":"Klajdi","family":"Puka","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5563-2377","authenticated-orcid":false,"given":"Kathy N.","family":"Speechley","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics Western University  London Ontario Canada"},{"name":"Department of Paediatrics, Schulich School of Medicine and Dentistry Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0979-3233","authenticated-orcid":false,"given":"Mark A.","family":"Ferro","sequence":"additional","affiliation":[{"name":"School of Public Health Sciences University of Waterloo  Waterloo Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary B.","family":"Connolly","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Pediatrics BC Children's Hospital  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0507-2543","authenticated-orcid":false,"given":"Philippe","family":"Major","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Neurosciences, CHU Sainte\u2010Justine Hospital University of Montreal  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9371-0495","authenticated-orcid":false,"given":"Anne","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Centre de Recherche, CHU Sainte\u2010Justine Hospital University of Montreal  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salah","family":"Almubarak","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Department of Pediatrics University of Saskatchewan  Saskatoon Saskatchewan Canada"},{"name":"Qatif Central Hospital  Qatif Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Hasal","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Department of Pediatrics University of Saskatchewan  Saskatoon Saskatchewan Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0368-8640","authenticated-orcid":false,"given":"Rajesh","family":"Ramachandrannair","sequence":"additional","affiliation":[{"name":"Department of Pediatrics McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Andrade","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Schulich School of Medicine and Dentistry Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6512-0631","authenticated-orcid":false,"given":"Qi","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health University of Manitoba  Winnipeg Manitoba Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3154-2403","authenticated-orcid":false,"given":"Edward","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health University of Manitoba  Winnipeg Manitoba Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"O. 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