{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T04:09:51Z","timestamp":1790914191573,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T00:00:00Z","timestamp":1710892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund","doi-asserted-by":"publisher","award":["KLI 969\u2010B"],"award-info":[{"award-number":["KLI 969\u2010B"]}],"id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Status epilepticus (SE) is frequently associated with peri\u2010ictal magnetic resonance imaging (MRI) abnormalities (PMA). However, the anatomical distribution of these alterations has not been systematically studied. The aim of this study was to assess the localization patterns of PMA in patients with SE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective case\u2013control study, we compared the distribution and combinations of diffusion\u2010restricted PMA to diffusion\u2010restricted lesions caused by other neurological conditions. All patients of the SE group and the control group underwent MRI including a diffusion\u2010weighted imaging sequence. Patients with SE were imaged within 48\u2009h after its onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We enrolled 201 patients (51 with SE and 150 controls). The most frequent locations of PMA in SE were cortex (25\/51, 49%), followed by hippocampus (20\/51, 39%) and pulvinar of thalamus (10\/51, 20%). In the control group, the cortex was involved in 80 of 150 (53%), white matter in 53 of 150 (35%), and basal ganglia in 33 of 150 (22%). In the control group, the pulvinar of thalamus was never affected and hippocampal structures were rarely involved (7\/150, 5%). Involvement of the pulvinar of thalamus and the hippocampus had high specificity for SE at 100% (95% confidence interval [CI] =\u200998\u2013100) and 95% (95% CI\u2009=\u200991\u201398), respectively. The sensitivity, however, was low for both locations (pulvinar of thalamus: 20%, 95% CI\u2009=\u200910\u201333; hippocampus: 39%, 95% CI\u2009=\u200926\u201354).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance<\/jats:title>\n                    <jats:p>Diffusion\u2010restricted MRI lesions observed in the pulvinar of thalamus and hippocampus are strongly associated with SE. These changes may help physicians in diagnosing SE\u2010related changes on MRI in an acute setting, especially in cases of equivocal clinical and electroencephalographic manifestations of SE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/epi.17949","type":"journal-article","created":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T11:09:35Z","timestamp":1710932975000},"page":"1620-1630","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["<scp>Magnetic resonance imaging<\/scp>\n                    fingerprints of status epilepticus: A case\u2013control study"],"prefix":"10.1111","volume":"65","author":[{"given":"Pilar","family":"Bosque\u00a0Varela","sequence":"first","affiliation":[{"name":"Department of Neurology, Christian Doppler University Hospital, member of the European Reference Network EpiCARE, Center for Cognitive Neuroscience Paracelsus Medical University of Salzburg  Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Payam","family":"Tabaee\u00a0Damavandi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Christian Doppler University Hospital, member of the European Reference Network EpiCARE, Center for Cognitive Neuroscience Paracelsus Medical University of Salzburg  Salzburg Austria"},{"name":"Department of Neurology, Fondazione IRCCS San Gerardo dei Tintori, School of Medicine and Surgery, Milan Center for Neuroscience University of Milano\u2010Bicocca  Monza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7437-8992","authenticated-orcid":false,"given":"Lukas","family":"Machegger","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Christian Doppler University Hospital Paracelsus Medical University of Salzburg  Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Pr\u00fcwasser","sequence":"additional","affiliation":[{"name":"Department of Neurology, Christian Doppler University Hospital, member of the European Reference Network EpiCARE, Center for Cognitive Neuroscience Paracelsus Medical University of Salzburg  Salzburg Austria"},{"name":"Department of Mathematics Paris\u2010Lodron University  Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8282-1034","authenticated-orcid":false,"given":"Georg","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Department of Mathematics Paris\u2010Lodron University  Salzburg Austria"},{"name":"Team Biostatistics and Big Medical Data, IDA Lab Salzburg Paracelsus Medical University  Salzburg Austria"},{"name":"Research and Innovation Management Paracelsus Medical University  Salzburg 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Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Pfaff","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Christian Doppler University Hospital Paracelsus Medical University of Salzburg  Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5950-2692","authenticated-orcid":false,"given":"Eugen","family":"Trinka","sequence":"additional","affiliation":[{"name":"Department of Neurology, Christian Doppler University Hospital, member of the European Reference Network EpiCARE, Center for Cognitive Neuroscience Paracelsus Medical University of Salzburg  Salzburg Austria"},{"name":"Neuroscience Institute Christian Doppler University Hospital  Salzburg Austria"},{"name":"Karl Landsteiner Institute for Neurorehabilitation and Space Neurology  Salzburg 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