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We assessed MVC features and the effect of epilepsy diagnosis on the risk of severe crash\u2010related injuries among drivers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 33\u2009174 MVC events among people with epilepsy (PWE) and 663\u2009480 MVC events of age\u2010 and sex\u2010matched non\u2010PWE (1:20) were selected. Crash\u2010related features that involved drivers with and without epilepsy were compared, including driver eligibility, medical history of comorbidities and medications, road and environmental conditions, and accident causes. Cox and logistic regression analyses were used to examine the risks of fatality and severe injury among drivers with and without epilepsy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PWE involved in MVCs were more likely to have lower socioeconomic status, comorbidities, scooter drivers without a qualified driver's license, driving under the influence of alcohol, and be involved in single\u2010vehicle accidents than non\u2010PWE. Drivers with epilepsy also had a higher risk of fatality within 30\u2009days of MVC, with an adjusted hazard ratio (aHR) of 1.37 (95% confidence interval [CI], 1.20\u20131.57) and a higher risk of hospital admission within 3\u2009days after MVC (aHR, 1.33; 95% CI, 1.29\u20131.38) compared to that of non\u2010PWE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>The characteristics of MVCs of drivers with epilepsy were distinct from those of non\u2010affected drivers. And higher fatality and injury rates were observed among drivers with epilepsy, which should be considered in further policymaking regarding safe driving of PWE.<\/jats:p><\/jats:sec>","DOI":"10.1111\/epi.18097","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T02:48:30Z","timestamp":1724294910000},"page":"2984-2994","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Characteristics of motor vehicle crashes and fatality risk among drivers with epilepsy"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4656-7032","authenticated-orcid":false,"given":"Yu","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Neurology En Chu Kong Hospital  New Taipei City Taiwan"},{"name":"Department of Neurology National Taiwan University Hospital, College of Medicine, National Taiwan University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng\u2010Yun","family":"Ku","sequence":"additional","affiliation":[{"name":"Graduate Institute of Data Science and Management, College of Management Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9644-3129","authenticated-orcid":false,"given":"Chih\u2010Ching","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Health Care Management National Taipei University of Nursing and Health Sciences  Taipei City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9441-552X","authenticated-orcid":false,"given":"Li\u2010Nien","family":"Chien","sequence":"additional","affiliation":[{"name":"Institute of Health and Welfare Policy, College of Medicine, National Yang Ming Chao Tung University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,21]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2013.09.024"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2015.04.016"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000500599"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2019.01.028"},{"issue":"91","key":"e_1_2_13_6_1","first-page":"e1102","article-title":"Characteristics of motor vehicle crashes associated with seizure: car crash semiology","volume":"18","author":"Neal A","year":"2018","journal-title":"Neurology"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2018.11.003"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2021.108046"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.16453"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000900"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01018.x"},{"key":"e_1_2_13_12_1","unstructured":"\u5168\u570b\u6cd5\u898f\u8cc7\u6599\u5eab. \u9055\u53cd\u9053\u8def\u4ea4\u901a\u7ba1\u7406\u4e8b\u4ef6\u7d71\u4e00\u88c1\u7f70\u57fa\u6e96\u53ca\u8655\u7406\u7d30\u5247. 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