{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:49:34Z","timestamp":1787014174321,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T00:00:00Z","timestamp":1729209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS126282"],"award-info":[{"award-number":["R01NS126282"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Here we critique recent arguments proposing to distinguish ictal from non\u2010ictal generalized periodic discharges (GPDs) based on etiology and stimulation response, arguing that these are unreliable. We advocate for an empirical approach to GPDs: describe objectively, interpret through medication trials, and base further treatment on response. We call for evidence\u2010based approaches considering meaningful clinical outcomes.<\/jats:p>","DOI":"10.1111\/epi.18159","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T08:03:41Z","timestamp":1729238621000},"page":"3484-3487","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Commentary on stimulus\u2010induced arousal with transient electroencephalographic improvement distinguishes nonictal from ictal generalized periodic discharges"],"prefix":"10.1111","volume":"65","author":[{"given":"Marcus C.","family":"Ng","sequence":"first","affiliation":[{"name":"Section of Neurology University of Manitoba  Winnipeg Manitoba Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5252-5376","authenticated-orcid":false,"given":"Sahar","family":"Zafar","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Foreman","sequence":"additional","affiliation":[{"name":"Neurology Department University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Kim","sequence":"additional","affiliation":[{"name":"School of Medicine Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron F.","family":"Struck","sequence":"additional","affiliation":[{"name":"University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4803-312X","authenticated-orcid":false,"given":"M. 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