{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T02:53:45Z","timestamp":1770778425581,"version":"3.50.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study was undertaken to determine whether admission to dedicated seizure monitoring units (SMUs) result in reduced health care use (HCU).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective open cohort study covering the years 2010\u20132018 of patients residing in Alberta, Canada, who were referred to the Calgary Comprehensive Epilepsy Program and admitted to a level 4 SMU. Patients were required to have \u22653\u2009years pre\u2010 and postadmission follow\u2010up. The outcome was the change in trajectory of composite HCU (primary care, specialist outpatient visits, emergency department visits, and hospitalizations) for the 3\u2009years prior to and 3\u2009years following SMU admission using the point of admission as the \u201cindex date.\u201d Secondary outcomes were HCU limited to specific settings. We excluded the first 30\u2009days following the point of admission to mitigate the confounding admission would have on the postadmission HCU trajectory. We used adjusted restricted maximum likelihood linear and nonlinear effects models to determine trajectories expressed as Canadian dollars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 315 of 600 (53%) patients met eligibility criteria. Mean age was 40\u2009years (SD\u2009=\u200917.4), 176 (56%) were female, 220 (70%) had focal epilepsy, and 60 (19%) had functional seizures or physiologic seizure mimics without epilepsy as adjudicated by the attending physician at the point of discharge. Mean per person health care costs increased by CAD$341.28 (95% confidence interval [CI] = \u221225.17 to 707.74) for each successive 6\u2010month interval prior to SMU admission (<jats:italic>p<\/jats:italic>\u2009=\u2009.07). Following admission, mean per person costs decreased by CAD$802.34 (95% CI\u2009=\u2009699.62\u2013905.06, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) for each successive 6\u2010month interval up to 3\u2009years postdischarge. Similar trends were noted for primary and specialist care, emergency department, admitted care, and when nonlinear models were applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>Admission to an SMU is associated with significant and enduring declines in HCU. Each 6\u2010months following discharge overall HCU declined by a mean of CAD$802.34 and acute inpatient, emergency department, and outpatient physician interactions declined by 25%, 26%, and 18% respectively. Comprehensive epilepsy care not only reduces morbidity and mortality but also reduces cost.<\/jats:p><\/jats:sec>","DOI":"10.1111\/epi.18165","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T14:28:20Z","timestamp":1731421700000},"page":"148-159","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Level 4 seizure monitoring unit admissions are associated with reduced long\u2010term health care costs"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7052-1651","authenticated-orcid":false,"given":"Colin B.","family":"Josephson","sequence":"first","affiliation":[{"name":"Department of Clinical Neurosciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Department of Community Health Sciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Hotchkiss Brain Institute, 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