{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:40:39Z","timestamp":1790300439699,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T00:00:00Z","timestamp":1733356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000295","name":"Epilepsy Research UK","doi-asserted-by":"publisher","award":["P1904"],"award-info":[{"award-number":["P1904"]}],"id":[{"id":"10.13039\/501100000295","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/Y016009\/1"],"award-info":[{"award-number":["EP\/Y016009\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["G0802012"],"award-info":[{"award-number":["G0802012"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/M00841X\/1"],"award-info":[{"award-number":["MR\/M00841X\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014013","name":"UK Research and Innovation","doi-asserted-by":"publisher","award":["MR\/T04294X\/1"],"award-info":[{"award-number":["MR\/T04294X\/1"]}],"id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014013","name":"UK Research and Innovation","doi-asserted-by":"publisher","award":["MR\/V026569\/1"],"award-info":[{"award-number":["MR\/V026569\/1"]}],"id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Magnetic resonance imaging (MRI) is a crucial tool for identifying brain abnormalities in a wide range of neurological disorders. In focal epilepsy, MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning and artificial intelligence (AI) algorithms may improve lesion detection if abnormalities are not evident on visual inspection. The success of this approach depends on the volume and quality of training data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Herein, we release an open\u2010source data set of pre\u2010processed MRI scans from 442 individuals with drug\u2010refractory focal epilepsy who had neurosurgical resections and detailed demographic information. We also share scans from 100 healthy controls acquired on the same scanners. The MRI scan data include the preoperative three\u2010dimensional (3D) T1 and, where available, 3D fluid\u2010attenuated inversion recovery (FLAIR), as well as a manually inspected complete surface reconstruction and volumetric parcellations. Demographic information includes age, sex, age a onset of epilepsy, location of surgery, histopathology of resected specimen, occurrence and frequency of focal seizures with and without impairment of awareness, focal to bilateral tonic\u2013clonic seizures, number of anti\u2010seizure medications (ASMs) at time of surgery, and a total of 1764 patient years of post\u2010surgical followup. Crucially, we also include resection masks delineated from post\u2010surgical imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>To demonstrate the veracity of our data, we successfully replicated previous studies showing long\u2010term outcomes of seizure freedom in the range of ~50%. Our imaging data replicate findings of group\u2010level atrophy in patients compared to controls. Resection locations in the cohort were predominantly in the temporal and frontal lobes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance<\/jats:title>\n                    <jats:p>We envisage that our data set, shared openly with the community, will catalyze the development and application of computational methods in clinical neurology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/epi.18192","type":"journal-article","created":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T11:29:25Z","timestamp":1733398165000},"page":"471-481","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["The Imaging Database for Epilepsy And Surgery (\n                    <scp>IDEAS<\/scp>\n                    )"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2144-9838","authenticated-orcid":false,"given":"Peter 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UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karoline","family":"Leiberg","sequence":"additional","affiliation":[{"name":"CNNP Lab (www.cnnp\u2010lab.com\/ideas\u2010data), Interdisciplinary Computing and Complex BioSystems Group, School of Computing Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Little","sequence":"additional","affiliation":[{"name":"CNNP Lab (www.cnnp\u2010lab.com\/ideas\u2010data), Interdisciplinary Computing and Complex BioSystems Group, School of Computing Newcastle University  Newcastle upon Tyne UK"},{"name":"Faculty of Medical Sciences Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Clifford","sequence":"additional","affiliation":[{"name":"CNNP Lab (www.cnnp\u2010lab.com\/ideas\u2010data), Interdisciplinary Computing and Complex BioSystems Group, School of Computing Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3978-7424","authenticated-orcid":false,"given":"Sophie","family":"Adler","sequence":"additional","affiliation":[{"name":"UCL Great Ormond Street Institute of Child Health  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjoerd B.","family":"Vos","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Centre for Medical Image Computing UCL  London UK"},{"name":"Centre for Microscopy, Characterisation, and Analysis The University of Western Australia  Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9395-1478","authenticated-orcid":false,"given":"Gavin P.","family":"Winston","sequence":"additional","affiliation":[{"name":"UCL Queen Square Institute of Neurology  London UK"},{"name":"Division of Neurology, Department of 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