{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T23:11:13Z","timestamp":1767913873137,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T00:00:00Z","timestamp":1373241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2014,1]]},"abstract":"Summary<\/jats:title>\n \n Reasons for performing study<\/jats:title>\n \n The bronchoalveolar lavage (\n BAL<\/jats:styled-content>\n ) procedure can return variable volumes of fluid, possibly depending on the presence of bronchial collapse during fluid aspiration and on the severity of lung inflammation.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n We tested the hypothesis that horses with bronchial collapse during\n BAL<\/jats:styled-content>\n are at higher risk of having severe lung inflammation.\n <\/jats:p>\n <\/jats:sec>\n \n Study design<\/jats:title>\n Prospective field study.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Bronchial collapse was graded using a new simple scoring method (0, 1 or 2) during a standardised\n BAL<\/jats:styled-content>\n procedure in the field on 131 horses with normal, mild\/moderate or severe lower airway inflammation on cytology of\n BAL<\/jats:styled-content>\n fluid.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of the 131 horses, 37 (28%), 55 (42%) and 39 (30%) horses had bronchial collapse scores of 0, 1 and 2, respectively. There was a difference in collapse scores between all the\n BAL<\/jats:styled-content>\n inflammation categories (P<0.001). Severe collapse had a positive predictive value of 0.95 for both mild\/moderate and severe\n BAL<\/jats:styled-content>\n inflammation, with a prevalence of 63% and 20%, respectively. The\n BAL<\/jats:styled-content>\n fluid return volume in the horses with severe collapse scores was lower than volumes in the partial (score 1\/2) and no collapse (score 0\/2) groups (P<0.001). The\n BAL<\/jats:styled-content>\n fluid volume was negatively correlated with\n BAL<\/jats:styled-content>\n neutrophil percentage (P<0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Airway collapse during\n BAL<\/jats:styled-content>\n is associated with airway inflammation and neutrophilia.\n <\/jats:p>\n <\/jats:sec>\n \n Potential relevance<\/jats:title>\n \n During a standardised\n BAL<\/jats:styled-content>\n procedure, clinicians can expect lung inflammation in horses that have bronchial collapse and bronchial collapse in horses with lung inflammation. Lung inflammation may be a contributing factor in the mechanism of bronchial collapse during\n BAL<\/jats:styled-content>\n in horses.\n <\/jats:p>\n \n \n The Summary is available in\n C<\/jats:styled-content>\n hinese \u2013 see Supporting information.\n <\/jats:bold>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/evj.12096","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T02:36:47Z","timestamp":1367807807000},"page":"50-55","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Bronchial collapse during bronchoalveolar lavage in horses is an indicator of lung inflammation"],"prefix":"10.1111","volume":"46","author":[{"given":"K.","family":"Koblinger","sequence":"first","affiliation":[{"name":"Moore Equine Veterinary Center Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Hecker","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine University of Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Nicol","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine University of Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Wasko","sequence":"additional","affiliation":[{"name":"Moore Equine Veterinary Center Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine University of Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"L\u00e9guillette","sequence":"additional","affiliation":[{"name":"Moore Equine Veterinary Center Alberta Canada"},{"name":"Faculty of Veterinary Medicine University of Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb02975.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516401776767412"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0739(02)00067-6"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.67.11.1929"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-66-4-651"},{"key":"e_1_2_11_7_1","first-page":"254","article-title":"The effects of chronic bronchitis and chronic air\u2010flow obstruction on lung cell populations recovered by bronchoalveolar lavage","volume":"132","author":"Martin T.R.","year":"1985","journal-title":"Am. 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