{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:37:22Z","timestamp":1762101442461,"version":"build-2065373602"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T00:00:00Z","timestamp":1378857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Reasons for performing the study<\/jats:title>\n                    <jats:p>\n                      Distal deep digital flexor tendinopathy is an important cause of foot lameness in horses that is difficult to diagnose with radiography and ultrasonography. Magnetic resonance imaging is a well\u2010accepted and validated technique for the identification of deep digital flexor tendon (\n                      <jats:styled-content style=\"fixed-case\">DDFT<\/jats:styled-content>\n                      ) lesions, but has some practical and financial drawbacks. Contrast\u2010enhanced computed tomography (\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      ) has been proposed as a suitable alternative, but validation studies are currently lacking.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To assess the accuracy of\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      for the identification and characterisation of deep digital flexor tendinopathy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>\n                      Descriptive study of\n                      <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\n                      , macroscopic and histological findings of the\n                      <jats:styled-content style=\"fixed-case\">DDFT<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Plain and\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      scans were acquired of 23 limbs of 16 horses with clinical lameness localised to the foot. All horses had lesions of the\n                      <jats:styled-content style=\"fixed-case\">DDFT<\/jats:styled-content>\n                      that were identified and characterised with\n                      <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      with respect to their anatomic location and extent. All horses underwent\n                      <jats:italic>post mortem<\/jats:italic>\n                      examination and gross abnormalities were described. Samples of the\n                      <jats:styled-content style=\"fixed-case\">DDFT<\/jats:styled-content>\n                      were taken at specific sites (lesion and nonlesion) for histological evaluation. Macroscopic and histological outcomes were compared with\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      findings.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 67 sites in 23\n                      <jats:styled-content style=\"fixed-case\">DDFTs<\/jats:styled-content>\n                      that were evaluated, 42 sites in 18 tendons had lesions on\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      images. These 42 sites also had lesions on macroscopic evaluation. There were 3 false negative and 3 false positive results identified on\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      . The sensitivity of\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      for diagnosing lesions of the\n                      <jats:styled-content style=\"fixed-case\">DDFT<\/jats:styled-content>\n                      in the equine foot was 93%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">CECT<\/jats:styled-content>\n                      is an effective adjunct to the more commonly used diagnostic techniques in equine foot pain.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/evj.12129","type":"journal-article","created":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T06:57:05Z","timestamp":1372661825000},"page":"300-305","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Contrast\u2010enhanced computed tomographic evaluation of the deep digital flexor tendon in the equine foot compared to macroscopic and histological findings in 23 limbs"],"prefix":"10.1111","volume":"46","author":[{"given":"S. E.","family":"van Hamel","sequence":"first","affiliation":[{"name":"Department of Equine Sciences Utrecht University  The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. J.","family":"Bergman","sequence":"additional","affiliation":[{"name":"Lingehoeve Diergeneeskunde  The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. M.","family":"Puchalski","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences University of California  USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. W.","family":"de Groot","sequence":"additional","affiliation":[{"name":"Department of Pathobiology Utrecht University  The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. 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