{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T17:47:03Z","timestamp":1780940823862,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,2,21]],"date-time":"2014-02-21T00:00:00Z","timestamp":1392940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100001655","name":"Grayson-Jockey Club Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001655","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100001250","name":"Morris Animal Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001250","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012221","name":"Lourie Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012221","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Maxwell H. Gluck Equine Research Center"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2014,11]]},"abstract":"Summary<\/jats:title>\n \n Reasons for performing study<\/jats:title>\n \n The sensitivity and specificity of lateral cervical radiographs to evaluate horses suspected of cervical stenotic myelopathy (\n CSM<\/jats:styled-content>\n ) are limited by the assessment being restricted to the sagittal plane.\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n \n To determine whether magnetic resonance imaging (\n MRI<\/jats:styled-content>\n ) allows for a more accurate identification of stenosis than lateral cervical radiographs in horses with\n CSM<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Study design<\/jats:title>\n Case control study.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Nineteen Thoroughbred horses with\n CSM<\/jats:styled-content>\n (17 males, 2 females, age 6\u201350 months) were compared to 9 control Thoroughbreds (6 males, 3 females, age 9\u201367 months).\n Ante mortem<\/jats:italic>\n , the subjects had neurological examinations and standing cervical radiographs with sagittal ratios calculated from\n C<\/jats:styled-content>\n 3 to\n C<\/jats:styled-content>\n 7. Intact cervical column\n MRI<\/jats:styled-content>\n scans and histological examinations of the spinal cord were performed\n post mortem<\/jats:italic>\n . Morphometric parameters were measured on the vertebral canal, spinal cord and intervertebral foramen.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Radiographic cervical canal height measurements categorised by standard minimal sagittal diameter intravertebral and intervertebral ratios produced several false positive and false negative determinations of canal stenosis as defined by spinal cord histopathology.\n Post mortem<\/jats:italic>\n \u2005\n MRI<\/jats:styled-content>\n measurements of canal area and cord canal area ratio more accurately predicted sites of cord compression in\n CSM<\/jats:styled-content>\n cases. No differences in spinal cord measurements were observed when comparing\n CSM<\/jats:styled-content>\n to control horses, but each of the vertebral canal parameters achieved significance at multiple sites.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Vertebral canal area and cord canal area ratio are better parameters to predict the location of cervical canal stenosis compared to only the sagittal plane of canal height. Additional visual planes and measurements obtained by\n MRI<\/jats:styled-content>\n , specifically vertebral canal area and the cord canal area ratio, will provide a more accurate method to identify regions of canal stenosis than lateral cervical radiographs. The development of\n MRI<\/jats:styled-content>\n or computed tomography equipment capable of evaluating the cervical column of mature horses may substantially enhance evaluation of\n CSM<\/jats:styled-content>\n patients.\n <\/jats:p>\n \n The Summary is available in Chinese \u2013 see Supporting information.<\/jats:bold>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/evj.12221","type":"journal-article","created":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T03:24:46Z","timestamp":1387164286000},"page":"681-686","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Comparison of magnetic resonance imaging with standing cervical radiographs for evaluation of vertebral canal stenosis in equine cervical stenotic myelopathy"],"prefix":"10.1111","volume":"46","author":[{"given":"J. G.","family":"Janes","sequence":"first","affiliation":[{"name":"Maxwell H. Gluck Equine Research Center Department of Veterinary Science University of Kentucky Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. S.","family":"Garrett","sequence":"additional","affiliation":[{"name":"Rood and Riddle Equine Hospital Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. J.","family":"McQuerry","sequence":"additional","affiliation":[{"name":"Department of Statistics University of Kentucky Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. P.","family":"Pease","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences Michigan State University College of Veterinary Medicine East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. M.","family":"Williams","sequence":"additional","affiliation":[{"name":"University of Kentucky Veterinary Diagnostic Laboratory, Department of Veterinary Science University of Kentucky Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M.","family":"Reed","sequence":"additional","affiliation":[{"name":"Rood and Riddle Equine Hospital Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. N.","family":"MacLeod","sequence":"additional","affiliation":[{"name":"Maxwell H. 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