{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T15:28:37Z","timestamp":1773329317319,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T00:00:00Z","timestamp":1401321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Rural Industries and Research Development Corporation"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2015,5]]},"abstract":"Summary<\/jats:title>\n \n Reasons for performing study<\/jats:title>\n \n Exercise\u2010induced pulmonary haemorrhage (\n EIPH<\/jats:styled-content>\n ) is associated with impaired short\u2010term race performance but consequences to long\u2010term race performance of Thoroughbred racehorses are unknown. Knowledge of effects of\n EIPH<\/jats:styled-content>\n on performance over a prolonged time would inform the need for management and treatment of this disorder.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n To determine the relationship between\n EIPH<\/jats:styled-content>\n detected on a single occasion and long\u2010term athletic performance in Thoroughbred racehorses.\n <\/jats:p>\n <\/jats:sec>\n \n Study design<\/jats:title>\n Prospective, longitudinal, observational epidemiological study conducted from 2003 to 2012.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Seven hundred and forty\u2010four Thoroughbred racehorses underwent a single tracheobronchoscopic examination to determine presence and severity of\n EIPH<\/jats:styled-content>\n in 2003. Following retirement of all the horses from racing, career after examination and lifetime performance data (including career duration, earnings, starts, wins and placings) were abstracted from a commercial database. The association between presence and severity of\n EIPH<\/jats:styled-content>\n and individual performance variables were analysed using survival analysis, linear regression and negative binomial regression.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n No association was detected between the presence of any\n EIPH<\/jats:styled-content>\n (\n grade<\/jats:italic>\n \u2265\n 1<\/jats:italic>\n ) and all measures of long\u2010term performance examined except that horses with\n EIPH<\/jats:styled-content>\n (\n grade<\/jats:italic>\n \u2265\n 2<\/jats:italic>\n ) had fewer earnings after endoscopic examination than did horses with mild\n EIPH<\/jats:styled-content>\n or no\n EIPH<\/jats:styled-content>\n (\n grades<\/jats:italic>\n \u2264\n 1<\/jats:italic>\n ). Multiple associations were detected between the most severe form of\n EIPH<\/jats:styled-content>\n (\n grade 4<\/jats:italic>\n ) and measures of long\u2010term performance suggesting that the severity of\n EIPH<\/jats:styled-content>\n commonly associated with epistaxis adversely affects either the horse's opportunity to race or physiologic capacity to race.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n We conclude that there is no association between\n EIPH<\/jats:styled-content>\n \u2005\n grades 0, 1, 2<\/jats:italic>\n and\n 3<\/jats:italic>\n and long\u2010term racing performance of Thoroughbred racehorses. These results are based on a single endoscopic evaluation of\n EIPH<\/jats:styled-content>\n grade made during a horse's career. Further studies are required to determine the reasons for an association of severe (\n grade 4<\/jats:italic>\n )\n EIPH<\/jats:styled-content>\n with impaired long\u2010term race performance.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/evj.12263","type":"journal-article","created":{"date-parts":[[2014,3,12]],"date-time":"2014-03-12T03:58:58Z","timestamp":1394596738000},"page":"350-357","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Prospective study of the association between exercise\u2010induced pulmonary haemorrhage and long\u2010term performance in\n T<\/scp>\n horoughbred racehorses"],"prefix":"10.1111","volume":"47","author":[{"given":"S. L.","family":"Sullivan","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Science University of Melbourne Werribee Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. A.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science University of Melbourne Werribee Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. S.","family":"Morley","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Colorado State University Fort Collins Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. W.","family":"Hinchcliff","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science University of Melbourne Werribee Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.227.768"},{"issue":"34","key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.2042-3306.2002.tb05451.x","article-title":"EIPH: postrace endoscopic evaluation of Standardbreds and Thoroughbreds","volume":"34","author":"Birks E.K.","year":"2002","journal-title":"Equine Vet. J."},{"key":"e_1_2_12_4_1","doi-asserted-by":"crossref","first-page":"772","DOI":"10.2460\/ajvr.1990.51.05.772","article-title":"Effects of furosemide on the racing times of Thoroughbreds","volume":"51","author":"Sweeney C.R.","year":"1990","journal-title":"Am. J. Vet. 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