{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:50:56Z","timestamp":1789685456131,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,9,5]],"date-time":"2014-09-05T00:00:00Z","timestamp":1409875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000982","name":"Rural Industries Research and Development Corporation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000982","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Racing Victoria Limited"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2015,7]]},"abstract":"Summary<\/jats:title>\n \n Reasons for performing study<\/jats:title>\n \n High\u2010resolution 3\n D<\/jats:styled-content>\n imaging may improve the prediction and\/or early identification of condylar fractures of the distal metacarpus\/tarsus and reduce the frequency of breakdown injury in racehorses.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n To test the hypotheses that horses suffering condylar fractures have higher bone volume fraction (\n BV<\/jats:styled-content>\n \/\n TV<\/jats:styled-content>\n ) of the distal metacarpal epiphysis, greater subchondral bone thickness at the fracture site and higher second moment of inertia in the metacarpal midshaft as identified with high\u2010resolution 3\n D<\/jats:styled-content>\n imaging.\n <\/jats:p>\n <\/jats:sec>\n \n Study design<\/jats:title>\n Cross\u2010sectional study using cadaver material.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Thoroughbreds that died on racetracks were grouped as: 1) horses with third metacarpal (\n McIII<\/jats:styled-content>\n ) fractures with a condylar component (cases, n = 13); 2) horses with no limb fracture (controls, n = 8); 3) horses with fractures in other bones or suspensory apparatus disruption (other fatal injuries, n = 16). The palmar condyles of\n McIII<\/jats:styled-content>\n and the midshaft were examined with high resolution peripheral quantitative computed tomography (\n HR<\/jats:styled-content>\n \u2010\n pQCT<\/jats:styled-content>\n ). Statistical analysis included logistic regression and Spearman's correlation.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n There were no significant differences in\n BV<\/jats:styled-content>\n \/\n TV<\/jats:styled-content>\n of distal\n McIII<\/jats:styled-content>\n and second moment of inertia of the midshaft between cases and controls. Epiphyseal bone\n BV<\/jats:styled-content>\n \/\n TV<\/jats:styled-content>\n was greater in injured limbs of horses with any fatal limb injury (\n Groups 1<\/jats:italic>\n and\n 3<\/jats:italic>\n combined) compared with controls (odds ratio = 1.20, 95% confidence interval 1.01\u20131.42, P = 0.034). An epiphyseal\n BV<\/jats:styled-content>\n \/\n TV<\/jats:styled-content>\n >0.742 resulted in a sensitivity of 82.8% and specificity of 62.5% in identifying horses with fatal limb injury. In horses without condylar fracture, increased subchondral bone thickness was associated with palmar osteochondral disease lesions in the adjacent condyle (r\n s<\/jats:sub>\n = 0.65, P<0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Increased\n BV<\/jats:styled-content>\n \/\n TV<\/jats:styled-content>\n of the distal metacarpus may have some value for identifying horses at risk of any fatal breakdown injury but not metacarpal condylar fractures. Measurement of parasagittal groove subchondral bone thickness is complicated by adjacent palmar osteochondral disease lesions. Thus, high\u2010resolution imaging of the distal metacarpus appears to have limited ability to identify horses at risk of condylar fractures.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/evj.12312","type":"journal-article","created":{"date-parts":[[2014,6,25]],"date-time":"2014-06-25T06:43:38Z","timestamp":1403678618000},"page":"428-432","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Can high\u2010resolution peripheral quantitative computed tomography imaging of subchondral and cortical bone predict condylar fracture in\n T<\/scp>\n horoughbred racehorses?"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1153-3772","authenticated-orcid":false,"given":"G. 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