{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:57:53Z","timestamp":1792292273427,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,8,12]],"date-time":"2017-08-12T00:00:00Z","timestamp":1502496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2018,1]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n \n There is limited information available concerning normal equine meniscal morphology, its degeneration and role in osteoarthritis (\n OA<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n To characterise normal equine meniscal morphology and lesions and to explore the relationship between equine meniscal degeneration and femorotibial\n OA<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Study design<\/jats:title>\n \n Ex vivo<\/jats:italic>\n cadaveric study.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Menisci were harvested from 7 normal joints (n = 14 menisci) and 15 joints with\n OA<\/jats:styled-content>\n (n = 30 menisci). A macroscopic femorotibial\n OA<\/jats:styled-content>\n score (cartilage degeneration and osteophytosis) was employed to measure disease severity in each compartment. The femoral and tibial meniscal surfaces were scored for macroscopic fibrillation and tears (1\u20134). Histological sections (regions: cranial and caudal horn; body) were also scored for microscopic fibrillation and tears (0\u20133) and inner border degeneration (0\u20133).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Partial meniscal tears were present on both femoral and tibial surfaces in all 3 regions and most frequently identified on the femoral surface of the cranial horn of the medial meniscus and body of the lateral meniscus. There was a significantly positive correlation between the global medial meniscal macroscopic scores and osteophyte (r = 0.7, P = 0.002) or cartilage degeneration (r = 0.5, P = 0.03) scores within the medial femorotibial joint. The global medial meniscal macroscopic score was greater (P = 0.004) in the advanced\n OA<\/jats:styled-content>\n joints compared with control joints.\n <\/jats:p>\n <\/jats:sec>\n \n Main limitations<\/jats:title>\n \n The menisci were principally from abattoir specimens without a known clinical history because of the challenge in obtaining a large number of specimens with a clinical diagnosis of femorotibial\n OA<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n This study is the first to describe normal equine meniscal morphology and lesions. Meniscal lesions were identified in all segments and on both articular surfaces. Meniscal degeneration significantly correlated with\n OA<\/jats:styled-content>\n severity in the equine medial femorotibial joint. The relationship between\n OA<\/jats:styled-content>\n and meniscal pathology remains to be elucidated.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/evj.12716","type":"journal-article","created":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T10:42:41Z","timestamp":1498905761000},"page":"133-140","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Equine meniscal degeneration is associated with medial femorotibial osteoarthritis"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0552-9117","authenticated-orcid":false,"given":"J.","family":"Dubuc","sequence":"first","affiliation":[{"name":"Comparative Orthopedic Research Laboratory Department of Clinical Sciences Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire Universit\u00e9 de Montr\u00e9al Saint\u2010Hyacinthe Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Girard","sequence":"additional","affiliation":[{"name":"Comparative Orthopedic Research Laboratory Department of Clinical Sciences Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire Universit\u00e9 de Montr\u00e9al Saint\u2010Hyacinthe Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Richard","sequence":"additional","affiliation":[{"name":"Comparative Orthopedic Research Laboratory Department of Clinical Sciences Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire Universit\u00e9 de Montr\u00e9al Saint\u2010Hyacinthe Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"De Lasalle","sequence":"additional","affiliation":[{"name":"Comparative Orthopedic Research Laboratory Department of Clinical Sciences Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire Universit\u00e9 de Montr\u00e9al Saint\u2010Hyacinthe Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Laverty","sequence":"additional","affiliation":[{"name":"Comparative Orthopedic Research Laboratory Department of Clinical Sciences Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire Universit\u00e9 de Montr\u00e9al Saint\u2010Hyacinthe Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.tvjl.2006.11.009","article-title":"Injuries in the event horse: training versus competition","volume":"175","author":"Singer E.R.","year":"2008","journal-title":"Vet. J."},{"key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.2042-3306.1982.tb02331.x","article-title":"Stifle lameness in the horse: a survey of 86 referred cases","volume":"14","author":"Jeffcott L.B.","year":"1982","journal-title":"Equine Vet. J."},{"key":"e_1_2_11_4_1","doi-asserted-by":"crossref","first-page":"402","DOI":"10.2746\/042516403776014163","article-title":"Meniscal tears in horses: an evaluation of clinical signs and arthroscopic treatment of 80 cases","volume":"35","author":"Walmsley J.R.","year":"2003","journal-title":"Equine Vet. J."},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/vru.12370","article-title":"Comparisons among radiography, ultrasonography and computed tomography for ex vivo characterization of stifle osteoarthritis in the horse","volume":"57","author":"De Lasalle J.","year":"2016","journal-title":"Vet. Radiol. 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Surg."},{"key":"e_1_2_11_23_1","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.2042-3306.2010.00291.x","article-title":"Meniscal translocation and deformation throughout the range of motion of the equine stifle joint: an in vitro cadaveric study","volume":"43","author":"Fowlie J.G.","year":"2011","journal-title":"Equine Vet. J."},{"key":"e_1_2_11_24_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1532-950X.2014.12242.x","article-title":"Ex vivo equine medial tibial plateau contact pressure with an intact medial femoral condyle, with a medial femoral condylar defect, and after placement of a transcondylar screw through the condylar defect","volume":"44","author":"Bonilla A.G.","year":"2015","journal-title":"Vet. Surg."},{"key":"e_1_2_11_25_1","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/j.2042-3306.2011.00532.x","article-title":"Stifle extension results in differential tensile forces developing between abaxial and axial components of the cranial meniscotibial ligament of the equine medial meniscus: a mechanistic explanation for meniscal tear patterns","volume":"44","author":"Fowlie J.G.","year":"2012","journal-title":"Equine Vet. J."},{"key":"e_1_2_11_26_1","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1002\/jor.22023","article-title":"Grand challenge competition to predict in vivo knee loads","volume":"30","author":"Fregly B.J.","year":"2012","journal-title":"J. Orthop. Res."},{"key":"e_1_2_11_27_1","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.2106\/JBJS.K.00927","article-title":"Influence of limb alignment on mediolateral loading in total knee replacement","volume":"94","author":"Halder A.","year":"2012","journal-title":"J. Bone Joint Surg."},{"key":"e_1_2_11_28_1","doi-asserted-by":"crossref","first-page":"3545","DOI":"10.1242\/jeb.01177","article-title":"Biomechanics of quadrupedal walking: how do four\u2010legged animals achieve inverted pendulum\u2010like movements?","volume":"207","author":"Griffin T.M.","year":"2004","journal-title":"J. Exp. Biol."},{"key":"e_1_2_11_29_1","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1177\/036354659101900302","article-title":"Tibial meniscal dynamics using three\u2010dimensional reconstruction of magnetic resonance images","volume":"19","author":"Thompson W.O.","year":"1991","journal-title":"Am. J. Sports Med."},{"key":"e_1_2_11_30_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1748-5827.1991.tb00524.x","article-title":"Meniscal damage associated with cruciate disease in the dog","volume":"32","author":"Bennett D.","year":"1991","journal-title":"J. Small Anim. Pract."},{"key":"e_1_2_11_31_1","doi-asserted-by":"crossref","first-page":"412","DOI":"10.2460\/ajvr.71.4.412","article-title":"Correlation of signal attenuation\u2010based quantitative magnetic resonance imaging with quantitative computed tomographic measurements of subchondral bone mineral density in metacarpophalangeal joints of horses","volume":"71","author":"Olive J.","year":"2010","journal-title":"Am. J. Vet. Res."},{"key":"e_1_2_11_32_1","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1016\/j.arthro.2005.08.031","article-title":"Is there an association between articular cartilage changes and degenerative meniscus tears?","volume":"21","author":"Christoforakis J.","year":"2005","journal-title":"Arthroscopy"},{"key":"e_1_2_11_33_1","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.joca.2016.10.025","article-title":"Cross\u2010sectional and longitudinal study of the impact of posterior meniscus horn lesions on adjacent cartilage composition, patient\u2010reported outcomes and gait biomechanics in subjects without radiographic osteoarthritis","volume":"25","author":"Russell C.","year":"2016","journal-title":"Osteoarthritis Cartilage"},{"key":"e_1_2_11_34_1","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1177\/0363546513490276","article-title":"The effects of meniscus injury on the development of knee osteoarthritis: data from the osteoarthritis initiative","volume":"41","author":"Badlani J.T.","year":"2013","journal-title":"Am. 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