{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:11:43Z","timestamp":1770221503230,"version":"3.49.0"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007904","name":"Texas A and M University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007904","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2018,1]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n \n Although rare, 70% of equine fatalities during recovery from general anaesthesia (\n GA<\/jats:styled-content>\n ) are due to catastrophic fractures from poor recovery quality.\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n \n To determine the effect of repeated\n GA<\/jats:styled-content>\n recovery on\n GA<\/jats:styled-content>\n recovery quality.\n <\/jats:p>\n <\/jats:sec>\n \n Study design<\/jats:title>\n Experimental blinded trial.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Eight adult horses underwent six\n GA<\/jats:styled-content>\n events on sevoflurane for distal limb\n MRI<\/jats:styled-content>\n examination over a 14\u2010week period. Prior to\n GA<\/jats:styled-content>\n recovery, xylazine was administered. Randomly ordered video\u2010recorded\n GA<\/jats:styled-content>\n recoveries were scored by three blinded board certified veterinary anaesthesiologists, unaware of patient identity or\n GA<\/jats:styled-content>\n event number, for nine parameters using a 100 mm visual analogue scale (\n VAS<\/jats:styled-content>\n ) where 0 = worst and 100 = best. The number of attempts to stand, duration of lateral and sternal recumbency, total recovery duration and physiologic parameters during each\n GA<\/jats:styled-content>\n event were recorded. Repeated measures\n ANOVA<\/jats:styled-content>\n were used to detect differences. Agreement between observer\n VAS<\/jats:styled-content>\n scores was determined via inter\u2010rater reliability using an intraclass correlation.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n With\n GA<\/jats:styled-content>\n recovery experience,\n VAS<\/jats:styled-content>\n scores for balance and coordination, knuckling, and overall quality of recovery were improved and the duration of lateral recumbency was increased. There were no differences in total recovery duration, number of attempts to stand, physiologic parameters other than heart rate during\n GA<\/jats:styled-content>\n , or\n VAS<\/jats:styled-content>\n scores for activity in lateral recumbency, move to sternal, move to stand, or strength.\n <\/jats:p>\n <\/jats:sec>\n \n Main limitations<\/jats:title>\n \n Each\n GA<\/jats:styled-content>\n event was relatively short and there was no surgical stimulation. The same results may not occur if there was surgical stimulation and pain during each\n GA<\/jats:styled-content>\n event.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Recovery from\n GA<\/jats:styled-content>\n improves with multiple anaesthetic episodes in horses. Clinicians can advise clients that horses are likely to have better\n GA<\/jats:styled-content>\n recovery on repeated\n GA<\/jats:styled-content>\n recovery due to improved balance and coordination and reduced knuckling. Additionally, there is no change in anaesthetic morbidity with six repeated\n GA<\/jats:styled-content>\n events over a 14\u2010week period.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/evj.12728","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T17:12:41Z","timestamp":1501780361000},"page":"111-116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The effects of multiple anaesthetic episodes on equine recovery quality"],"prefix":"10.1111","volume":"50","author":[{"given":"J. P.","family":"Platt","sequence":"first","affiliation":[{"name":"Comparative Orthopedics and Regenerative Medicine Laboratory Department of Large Animal Clinical Sciences Texas A&M University College Station Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. 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