{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T09:13:08Z","timestamp":1783415588625,"version":"3.54.6"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,8,25]],"date-time":"2018-08-25T00:00:00Z","timestamp":1535155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["11\/PI\/1166"],"award-info":[{"award-number":["11\/PI\/1166"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      We hypothesised that grade\/appearance for upper respiratory tract (\n                      <jats:styled-content style=\"fixed-case\">URT<\/jats:styled-content>\n                      ) disorders identified at the first overground endoscopy (\n                      <jats:styled-content style=\"fixed-case\">OGE<\/jats:styled-content>\n                      ) examination would vary at subsequent examinations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To compare\n                      <jats:styled-content style=\"fixed-case\">OGE<\/jats:styled-content>\n                      examinations from horses evaluated on at least two occasions under similar exercise conditions without treatment intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Retrospective cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Pre\u2010exercise and exercising\n                      <jats:styled-content style=\"fixed-case\">OGE<\/jats:styled-content>\n                      recordings from Thoroughbred horses undergoing multiple examinations under similar exercise conditions were reviewed, with the first two recordings for each horse statistically evaluated. Paired Wilcoxon signed\u2010rank tests were used to assess differences in exercise and physiological parameters between examinations. Z\u2010tests were used to assess the proportion of changes in\n                      <jats:styled-content style=\"fixed-case\">URT<\/jats:styled-content>\n                      disorder grade\/appearance between examinations. A McNemar's test was used to compare the proportion of horses with each disorder at each examination. Test\u2013retest reliability across examinations was assessed using Spearman's \u03c1, and ordered logistic regression used to explore temporal effects on repeatability. Lattice plots were constructed to view variability in disorders over time.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventy\u2010eight horses (median age 2.4 years) with 195 resting endoscopic examinations including 72\/78 horses with 179 pre\u2010exercise and exercising\n                      <jats:styled-content style=\"fixed-case\">OGE<\/jats:styled-content>\n                      examinations were evaluated. Median time between examinations was 226.5 days with no differences between exercise and physiological parameters. Grades significantly varied between examinations for all disorders, and in particular for palatal instability (\n                      <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>\n                      ) and epiglottic grade at rest. A temporal link between examination interval and disorder grade change was identified for\n                      <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>\n                      and resting arytenoid asymmetry.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main limitations<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">OGE<\/jats:styled-content>\n                      re\u2010examinations within a shorter, more consistent time\u2010frame would allow determination of intrahorse variability. The sample size was inadequate to conclusively establish temporal links between disorders and time between examinations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Variability for most\n                      <jats:styled-content style=\"fixed-case\">URT<\/jats:styled-content>\n                      abnormalities identified with\n                      <jats:styled-content style=\"fixed-case\">OGE<\/jats:styled-content>\n                      should be considered when making therapeutic decisions based on a single examination and may partially explain development of additional\n                      <jats:styled-content style=\"fixed-case\">URT<\/jats:styled-content>\n                      conditions after surgical intervention.\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:bold>The Summary is available in Portuguese \u2010 see Supporting Information<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/evj.12994","type":"journal-article","created":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T03:15:21Z","timestamp":1531451721000},"page":"192-197","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Serial evaluation of resting and exercising overground endoscopic examination results in young Thoroughbreds with no treatment intervention"],"prefix":"10.1111","volume":"51","author":[{"given":"C. L.","family":"McGivney","sequence":"first","affiliation":[{"name":"UCD School of Agriculture and Food Science University College Dublin Belfield, Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Sweeney","sequence":"additional","affiliation":[{"name":"UCD School of Business University College Dublin Belfield, Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0040-1958","authenticated-orcid":false,"given":"K. F.","family":"Gough","sequence":"additional","affiliation":[{"name":"UCD School of Agriculture and Food Science University College Dublin Belfield, Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1805-2250","authenticated-orcid":false,"given":"E. W.","family":"Hill","sequence":"additional","affiliation":[{"name":"UCD School of Agriculture and Food Science University College Dublin Belfield, Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5547-2089","authenticated-orcid":false,"given":"L. M.","family":"Katz","sequence":"additional","affiliation":[{"name":"UCD, School of Veterinary Medicine University College Dublin Belfield, Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2746\/042516406778400619","article-title":"Dynamic obstructions of the equine upper respiratory tract. Part 2: comparison of endoscopic findings at rest and during high\u2010speed treadmill exercise of 600 Thoroughbred racehorses","volume":"38","author":"Lane J.G.","year":"2006","journal-title":"Equine Vet. 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