{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:57:33Z","timestamp":1792292253478,"version":"4.4.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,8,21]],"date-time":"2018-08-21T00:00:00Z","timestamp":1534809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008605","name":"RCVS Knowledge","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008605","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      There is little knowledge of the prescription of nonsteroidal anti\u2010inflammatory drugs (\n                      <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>\n                      s) and whether their prescription varies between countries.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To describe prescription practices of\n                      <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>\n                      s in equids in the United Kingdom (\n                      <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>\n                      ), United States of America (\n                      <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content>\n                      ) and Canada.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Descriptive observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Free\u2010text electronic medical records from 141,543 equids from 10 equine practices in the\n                      <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>\n                      , 255,777 equids from 7 equine practices with 20 branches from the\n                      <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content>\n                      and 2 practices with 7 branches from Canada were evaluated. A validated text\u2010mining technique was used to describe the proportion of equids prescribed\n                      <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>\n                      s at least once in these countries. The choice of\n                      <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>\n                      s in orthopaedic and colic cases was evaluated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The prescription of\n                      <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>\n                      s is more common in the\n                      <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content>\n                      (42.4%) and Canada (34.2%) than in the\n                      <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>\n                      (28.6%). Phenylbutazone and flunixin meglumine were the drugs mostly prescribed in all countries. While flunixin meglumine was most prescribed with colic cases in all countries, a proportion received phenylbutazone despite this drug being licensed for use only with musculoskeletal disease. Phenylbutazone was the most commonly prescribed drug in cases with orthopaedic disease followed by flunixin meglumine in all countries. Only a small proportion of cases received meloxicam, ketoprofen or firocoxib.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main limitations<\/jats:title>\n                    <jats:p>The retrospective design might have resulted in an unknown number of incomplete records, particularly in the reporting of colic and orthopaedic disease. Although the data set is large, the relatively small number of practices recruited from each country may introduce bias.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Clinical practice can differ between countries although the influence of individual practitioners and practice\u2010specific policy on apparent intercountry differences requires further research. Despite several other\n                      <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>\n                      s being available and a substantial effort being made to evaluate their efficacy, the prescription of\n                      <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>\n                      s other than phenylbutazone and flunixin meglumine remains rather limited.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/evj.12997","type":"journal-article","created":{"date-parts":[[2018,7,26]],"date-time":"2018-07-26T10:38:43Z","timestamp":1532601523000},"page":"147-153","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Proportion of nonsteroidal anti\u2010inflammatory drug prescription in equine practice"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5016-4810","authenticated-orcid":false,"given":"M.","family":"Duz","sequence":"first","affiliation":[{"name":"Weipers Centre Equine Hospital School of Medical, Veterinary and Life Sciences University of Glasgow Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8344-2589","authenticated-orcid":false,"given":"J. F.","family":"Marshall","sequence":"additional","affiliation":[{"name":"Weipers Centre Equine Hospital School of Medical, Veterinary and Life Sciences University of Glasgow Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3566-9030","authenticated-orcid":false,"given":"T. D.","family":"Parkin","sequence":"additional","affiliation":[{"name":"Weipers Centre Equine Hospital School of Medical, Veterinary and Life Sciences University of Glasgow Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1996.tb15405.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4102\/jsava.v72i1.613"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2987.2004.00175.x"},{"key":"e_1_2_11_5_1","first-page":"715","article-title":"Pain recognition and treatment in the horse: a survey of equine veterinarians in the Netherlands and Belgium","volume":"136","author":"Dujardin C.L.L.","year":"2011","journal-title":"Tijdschr. 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