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As such, it is important to understand the mechanisms of these diseases and how they are diagnosed. These diseases include haemophilia A, von Willebrand disease, prekallikrein deficiency, Glanzmann's Thrombasthenia and Atypical Equine Thrombasthenia. Exercise\u2010induced pulmonary haemorrhage also has a proposed genetic component. Genetic mutations have been identified for haemophilia A and Glanzmann's Thrombasthenia in the horse. Mutations are known for von Willebrand disease and prekallikrein deficiency in other species. In the absence of genetic tests, bleeding disorders are typically diagnosed by measuring platelet function, von Willebrand factor, and other coagulation protein levels and activities. For autosomal recessive diseases, genetic testing can prevent the breeding of two carriers.<\/jats:p>","DOI":"10.1111\/evj.13290","type":"journal-article","created":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T13:51:38Z","timestamp":1590673898000},"page":"30-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Genetics of equine bleeding disorders"],"prefix":"10.1111","volume":"53","author":[{"given":"Anna R.","family":"Dahlgren","sequence":"first","affiliation":[{"name":"Population Health and Reproduction School of Veterinary Medicine University of California Davis CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fern","family":"Tablin","sequence":"additional","affiliation":[{"name":"Physiology and Cell Biology School of Veterinary Medicine University of California Davis CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5924-0234","authenticated-orcid":false,"given":"Carrie J.","family":"Finno","sequence":"additional","affiliation":[{"name":"Population Health and Reproduction School of Veterinary Medicine University of California Davis CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,23]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"327","volume-title":"Laboratory Test Handbook","author":"Van Cott EM","year":"2001"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-011-0290-8"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.2011.00338.x"},{"key":"e_1_2_12_5_1","first-page":"78","article-title":"Hemostasis","volume":"4","author":"Alcott C","year":"2009","journal-title":"Compend Contin Educ Pract Vet (Equine Ed)"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.0019.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.12315"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1991.tb02719.x"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1977.tb03959.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1967.tb08888.x"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.91.26.655"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1962.tb06539.x"},{"key":"e_1_2_12_13_1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2460\/javma.1988.193.01.91","article-title":"Hemophilia A in two related quarter horse colts","volume":"193","author":"Henninger RW","year":"1988","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_12_14_1","first-page":"24","article-title":"Hemophilia A (factor Vlll deficiency) in a colt","volume":"4","author":"Feldman BF","year":"1982","journal-title":"Equine Pract"},{"key":"e_1_2_12_15_1","first-page":"259","article-title":"Hemophilia in a foal","volume":"144","author":"Sanger VL","year":"1964","journal-title":"J Am Med Assoc"},{"key":"e_1_2_12_16_1","first-page":"338","article-title":"True haemophilia (haemophilia A) in a Thoroughbred foal","volume":"73","author":"Archer RK","year":"1961","journal-title":"Vet Rec"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1983.tb05869.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-79-19488"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-82-20057"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.24.10095"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V88.9.3451.bloodjournal8893451"},{"key":"e_1_2_12_22_1","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.2460\/javma.1997.211.11.1418","article-title":"Complete deletion of factor IX gene and inhibition of factor IX activity in a labrador retriever with hemophilia B","volume":"211","author":"Brooks MB","year":"1997","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1614374"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00335-003-2290-z"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2005.tb02682.x"},{"key":"e_1_2_12_26_1","unstructured":"Centers for Disease Control and Prevention.CDC Hemophilia Mutation Project.2018. 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