{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:11:20Z","timestamp":1790187080808,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T00:00:00Z","timestamp":1642723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although survival rates have been reported after small intestinal surgery for strangulating diseases in horses, none have followed survival for periods relevant to the long lifespan of horses and none have described effect of age, disease and surgical treatments over such long survival periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine effects of age, disease and type of surgery on long\u2010term survival in horses after surgical treatment of small intestinal strangulating diseases over periods relevant to the expected lifespan of a horse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective clinical study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Post\u2010operative data were gathered from medical records and owner contact for 89 horses with small intestinal strangulation. Survival times from surgery to the date of death or the date of last follow\u2010up were analysed by Kaplan\u2010Meier statistics. Variables of interest were age, type of strangulating disease and surgical correction. Cox proportional hazards regression was used to evaluate these variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Short\u2010term survival was not affected by any of the variables measured. For long\u2010term survival with Kaplan\u2010Meier statistics, horses \u226516\u00a0years old had significantly shorter (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.002) median survival times (72\u00a0months; 95% CI 32.0\u201096.0) than younger horses (121.7\u00a0months; 95% CI 90.0\u2010162), horses without resection had significantly longer (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.02) survival times (120\u00a0months; 95% CI 86\u2010212) than horses that had jejunocecostomy (76.8\u00a0months; 95% CI 24\u2010125), and horses with miscellaneous diseases had significantly longer (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.02) median survival times (161.9\u00a0months; 95% CI 72.0\u2010M) than horses with strangulating lipoma (79.8\u00a0months; 95% CI 32.0\u2010120.0). In the multivariable Cox Proportional Hazard model, age (HR\u00a0=\u00a02.67; 1.49\u20104.75,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001) and anastomosis (HR\u00a0=\u00a00.65; 0.46\u20100.92,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.02) had the most significant effect on median survival time.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Limitations<\/jats:title>\n                    <jats:p>Limitations were small numbers in some categories, loss of cases to follow\u2010up, owner recall failures and lack of a control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The remaining lifespan of older horses at the time of surgery had the greatest effect on survival. Age could influence long\u2010term survival studies after colic surgery, and therefore needs to be considered for survival analyses. Horses that did not require resection and anastomosis had favourable outcomes, underscoring the potential importance of early intervention to reduce the need for resection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/evj.13558","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:59:11Z","timestamp":1642035551000},"page":"1031-1038","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Effects of age, disease and anastomosis on short\u2010 and long\u2010term survival after surgical correction of small intestinal strangulating diseases in 89 horses"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5480-2194","authenticated-orcid":false,"given":"Meredith J.","family":"Rudnick","sequence":"first","affiliation":[{"name":"Department of Large Animal Clinical Sciences University of Florida College of Veterinary Medicine  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas N.","family":"Denagamage","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences University of Florida College of Veterinary Medicine  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7777-7569","authenticated-orcid":false,"given":"David E.","family":"Freeman","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences University of Florida College of Veterinary Medicine  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1751-0147-56-38"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12281.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.235.9.1069"},{"issue":"32","key":"e_1_2_10_5_1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.2042-3306.2000.tb05333.x","article-title":"Short\u2010 and long\u2010term survival and prevalence of postoperative ileus after small intestinal surgery in the horse","volume":"32","author":"Freeman DE","year":"2000","journal-title":"Equine Vet J"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2010.00085.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.87"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2020.103012"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13013"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2004.09.005"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776117881"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13028-016-0273-9"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164054529481"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12143"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2008.00479.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12143.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13161"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2011.06.002"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.223.93"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164054529436"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776117845"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2011.00409.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516407X171354"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1990.tb01116.x"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.237.9.1060"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12216"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12817"},{"key":"e_1_2_10_28_1","first-page":"729","article-title":"Einige seltene Magen\u2010 und Duodenum\u2010erkrankungen beim erwachsenen Pferd: Zweiphasige Magenruptur, chronische Magendilatation, Duodenumdilatation mit Hypo\u2010oder Aganglionose, L\u00e4ngsachsendrehung des Duodenum","volume":"81","author":"Huskamp B","year":"2000","journal-title":"Prakt Tierarzt"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601118"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1976.220"},{"key":"e_1_2_10_31_1","volume-title":"Survival analysis: a self\u2010learning text","author":"Kleinbaum DGD","year":"2011"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12256.x"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12493"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776117746"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.249.6.660"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13081"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.1529"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2008.00420.x"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12664"},{"key":"e_1_2_10_40_1","unstructured":"USDA. 2016. Equine 2015 \u201cBaseline Reference of Equine Health and Management in the United States 2015\u201d USDA\u2013APHIS\u2013VS\u2013CEAH\u2013NAHMS. Fort Collins CO #718.1216."}],"container-title":["Equine Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/evj.13558","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/evj.13558","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/beva.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/evj.13558","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T07:51:16Z","timestamp":1762069876000},"score":1,"resource":{"primary":{"URL":"https:\/\/beva.onlinelibrary.wiley.com\/doi\/10.1111\/evj.13558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,21]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/evj.13558"],"URL":"https:\/\/doi.org\/10.1111\/evj.13558","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/EVJ.13558\/v4\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v4\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v3\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v4\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.13558\/v3\/decision1","asserted-by":"object"}]},"ISSN":["0425-1644","2042-3306"],"issn-type":[{"value":"0425-1644","type":"print"},{"value":"2042-3306","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,21]]},"assertion":[{"value":"2021-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}