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While CHDs are rare in the general horse population, the Arabian breed is disproportionately overrepresented and thus is widely suspected to be genetically predisposed. This review discusses the most common CHDs in Arabian horses, including ventricular septal defect (VSD), tetralogy of Fallot (TOF), patent duct arteriosus (PDA), tricuspid valve atresia (TVA) and atrial septal defect (ASD). This review also explores how future research into the genetic factors that likely underpin many CHDs can revolutionise the way these disorders are managed in Arabian horses.<\/jats:p>","DOI":"10.1111\/evj.14062","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T22:43:10Z","timestamp":1706222590000},"page":"884-891","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Congenital heart defects in Arabian horses and the prospects of genetic testing: A review"],"prefix":"10.1111","volume":"56","author":[{"given":"Caitlin","family":"Brown","sequence":"first","affiliation":[{"name":"Equine Genetics and Genomics Group, School of Life and Environmental Sciences, University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4158-771X","authenticated-orcid":false,"given":"Monika","family":"Stefaniuk\u2010Szmukier","sequence":"additional","affiliation":[{"name":"Department of Animal Molecular Biology National Research Institute of Animal Production  Balice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8129-2006","authenticated-orcid":false,"given":"Annelies","family":"Decloedt","sequence":"additional","affiliation":[{"name":"Equine Cardioteam Ghent, Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine Ghent University  Merelbeke Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niek","family":"Beijerink","sequence":"additional","affiliation":[{"name":"Veterinaire Specialisten Vught  Vught The Netherlands"},{"name":"Sydney School of Veterinary Science, Faculty of Science University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha A.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Sydney School of Veterinary Science, Faculty of Science University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9359-6138","authenticated-orcid":false,"given":"Brandon D.","family":"Velie","sequence":"additional","affiliation":[{"name":"Equine Genetics and Genomics Group, School of Life and Environmental Sciences, University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-2817-5.00020-1"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1978.172.07.825"},{"key":"e_1_2_12_4_1","first-page":"187","article-title":"Right atrioventricular atresia and ventricular septal defect in a foal","volume":"77","author":"Wilson RB","year":"1987","journal-title":"Cornell Vet"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098588001700511"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098588201900207"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1997.tb01661.x"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1079\/AHR200353"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2009.0445.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2016.04.002"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2018.11.001"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1995.tb04994.x"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2019.04.012"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2020.03.004"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2020.103200"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9013239"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1982.181.07.684"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0264.1989.tb00594.x"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.2001.tb00112.x"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/vms3.317"},{"key":"e_1_2_12_21_1","unstructured":"MorganE OntiverosE EstellK SternJ.Identification of genetic markers for ventricular septal defects in Arabian horses. 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