{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T17:00:35Z","timestamp":1762102835272,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Post\u2010operative reflux (POR) is rare following large colon volvulus (LCV) but does occur despite the absence of a small intestinal lesion. The prevalence, risk factors and association with survival of POR after LCV are currently unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the prevalence of POR in horses with an LCV and its association with survival. A further objective was to assess factors which may predict POR. The hypothesis was that horses with POR following LCV surgery have a worse outcome for survival compared to those without POR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>A retrospective cross\u2010sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Clinical data of client owned horses which underwent colic surgery at a single UK referral hospital between 2008 and 2021, where LCV was the primary finding, were retrieved from hospital records. Statistical analyses included chi\u2010squared,\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests and odds ratios (ORs). Horses with concurrent lesions, and those that did not survive past anaesthetic recovery, were excluded from analysis. POR was defined as \u22652\u2009L of gastric reflux on at least one occasion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 128 horses were included in the study, 23 of which had POR (18%). Overall survival to hospital discharge was 86%, 95% in the non\u2010POR and 44% in the POR group. Horses with POR were less likely to survive to discharge than those without (OR\u2009=\u200926, 95% confidence interval [CI] [7.68\u201388.0],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and less likely to be alive 3\u2009years after surgery (OR\u2009=\u200913.4, 95% CI [2.78\u201364.8],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main limitations<\/jats:title>\n                    <jats:p>Due to the retrospective study design, full data sets were not available for every case because clinical records were incomplete or, at that time, certain tests were not performed or clinical variables were not measured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>POR in LCV cases is a negative prognostic indicator for survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/evj.14095","type":"journal-article","created":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T01:34:51Z","timestamp":1712972091000},"page":"1155-1161","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Factors associated with development of post\u2010operative reflux in horses with large colon volvulus and association with complications and outcomes"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7077-0756","authenticated-orcid":false,"given":"Natalia","family":"Watrobska","sequence":"first","affiliation":[{"name":"Donnington Grove Veterinary Group  Newbury UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0506-0358","authenticated-orcid":false,"given":"Rachel","family":"Gough","sequence":"additional","affiliation":[{"name":"Donnington Grove Veterinary Group  Newbury UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2294-6502","authenticated-orcid":false,"given":"Gayle","family":"Hallowell","sequence":"additional","affiliation":[{"name":"Equine Medicine University of Nottingham  Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1787-134X","authenticated-orcid":false,"given":"Simon","family":"Haugaard","sequence":"additional","affiliation":[{"name":"University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5801-1461","authenticated-orcid":false,"given":"Kate F.","family":"McGovern","sequence":"additional","affiliation":[{"name":"Donnington Grove Veterinary Group  Newbury UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776117845"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164054529409"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12039"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2012.00620.x"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12281.x"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2008.00479.x"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.72"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13217"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1986.tb03623.x"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2009.0311.x"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.225.1070"},{"key":"e_1_2_13_13_1","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.2460\/javma.1994.205.12.1748","article-title":"Evaluation of factors associated with postoperative ileus in horses: 31 cases (1990\u20101992)","volume":"205","author":"Blikslager AT","year":"1994","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164054529364"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.12396"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776117791"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-10-746479"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-304176"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.169250"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i44.5523"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2010.00246.x"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.08.036"},{"key":"e_1_2_13_23_1","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/B1-41-600123-9\/50038-3","volume-title":"Equine surgery","author":"Rakestraw PC","year":"2006"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516409X464122"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12776"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516409X456040"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164054529445"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776117881"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516408X293529"}],"container-title":["Equine Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/beva.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/evj.14095","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T12:33:51Z","timestamp":1762086831000},"score":1,"resource":{"primary":{"URL":"https:\/\/beva.onlinelibrary.wiley.com\/doi\/10.1111\/evj.14095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,12]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/evj.14095"],"URL":"https:\/\/doi.org\/10.1111\/evj.14095","archive":["Portico"],"relation":{},"ISSN":["0425-1644","2042-3306"],"issn-type":[{"type":"print","value":"0425-1644"},{"type":"electronic","value":"2042-3306"}],"subject":[],"published":{"date-parts":[[2024,4,12]]},"assertion":[{"value":"2023-05-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}