{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T18:30:31Z","timestamp":1789583431956,"version":"build-2803163510"},"reference-count":52,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is controversy about the clinical relevance of congenital variants of the ventral laminae of the sixth (C6) and seventh (C7) cervical vertebrae and their relationship with other radiological abnormalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To document the prevalence of congenital variants of C6 and C7 and that of other radiological abnormalities from C6 to the second thoracic vertebra (T2).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Cross\u2010sectional.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study included Warmblood horses \u22653\u2009years of age undergoing clinical assessment at two referral institutions: 127 control horses and 96 cases (neurologic, neck pain or stiffness, or neck\u2010related forelimb lameness). All horses underwent a standardised orthopaedic and neurologic examination. Lateral\u2013lateral and lateral 45\u00b0\u201355\u00b0 ventral\u2013lateral dorsal (left to right and right to left) radiographic views of C5 to T2 were acquired and assessed blinded to the horse's clinical category using a predetermined grading system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The ventral profile of C7 was abnormal in 54 horses (24.2%). Cases were less likely to have congenital variants than control horses,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0002, relative risk (RR): 0.63 (95% confidence intervals [CIs]: 0.4, 1.0). There was no association between the presence of a congenital variant of C7 and the presence of modelling of the articular processes (APs) of C6\u2013C7, C7\u2013T1 or T1\u2013T2. Cases were more likely to have severe modelling of the APs at C6\u2013C7,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01, RR: 1.94, CI: 1.1, 3.5 and C7\u2013T1,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04, RR: 1.97, CI: 1.2, 3.2 compared with control horses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main limitations<\/jats:title>\n                    <jats:p>Radiographs were read by one assessor independently at each institution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There was no association between the presence of congenital variants of C7 and any other radiological findings. Congenital variants occurred less frequently in cases compared with control horses. There was no association between the presence or absence of a congenital variant and the type of case.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/evj.14127","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T03:47:07Z","timestamp":1719546427000},"page":"419-430","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Congenital variants of the ventral laminae of the sixth and seventh cervical vertebrae are not associated with clinical signs or other radiological abnormalities of the cervicothoracic region in Warmblood horses"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4774-7497","authenticated-orcid":false,"given":"Sue","family":"Dyson","sequence":"first","affiliation":[{"name":"Independent Consultant  Diss UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9810-9607","authenticated-orcid":false,"given":"Kathryn","family":"Phillips","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences School of Veterinary Medicine University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shichen","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Medicine and Epidemiology University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5811-9520","authenticated-orcid":false,"given":"Monica","family":"Aleman","sequence":"additional","affiliation":[{"name":"Department of Medicine and Epidemiology University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1993.tb02984.x"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.237.7.812"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.233.9.1453"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2011.08.005"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.12411"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12350"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13140"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.12980"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve\/13125"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2020.103176"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1987.tb02568.x"},{"key":"e_1_2_15_13_1","first-page":"355","volume-title":"Clinical radiology of the horse","author":"Butler J","year":"1993"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2014.09.012"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2015.03.002"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12397"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12393"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.105756"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.21836\/PEM20210606"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13142384"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13213415"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13233732"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13383"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.21836\/PEM20220601"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516409X391015"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.20.03.0105"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13158"},{"key":"e_1_2_15_28_1","unstructured":"Nomina Anatomica Veterinaria.Prepared by the International Committee on Veterinary Gross Anatomical Nomenclature. Published by the Editorial Committee Hanover (Germany) Ghent (Belgium) Columbia MO (U.S.A.) Rio de Janeiro (Brazil).2017."},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13420"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.17125"},{"key":"e_1_2_15_31_1","first-page":"531","volume-title":"Clinical radiology of the horse","author":"Butler J","year":"2017"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870101300401"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12913"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.13375"},{"key":"e_1_2_15_35_1","first-page":"21","volume-title":"Physical therapy and massage for the horse","author":"Denoix J\u2010M","year":"1996"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1082"},{"key":"e_1_2_15_37_1","unstructured":"RombachN.The structural basis of equine neck pain. PhD thesis. Michigan State University East Lansing.2013."},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0222989"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.75.5.433"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2010.00226.x"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2010.00265.x"},{"key":"e_1_2_15_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.13350"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13410"},{"key":"e_1_2_15_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15848"},{"key":"e_1_2_15_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.1374"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13681"},{"key":"e_1_2_15_47_1","first-page":"437","article-title":"How to obtain and evaluate oblique projection radiographs of the equine cervical spine","volume":"64","author":"Werpy N","year":"2018","journal-title":"Proc Am Assoc Equine Pract"},{"key":"e_1_2_15_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12794"},{"key":"e_1_2_15_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13229"},{"key":"e_1_2_15_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani10040667"},{"key":"e_1_2_15_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7216-8342-3.50019-X"},{"key":"e_1_2_15_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2016.09.013"},{"key":"e_1_2_15_53_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.253.5.611"}],"container-title":["Equine Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/beva.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/evj.14127","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T13:18:17Z","timestamp":1762089497000},"score":1,"resource":{"primary":{"URL":"https:\/\/beva.onlinelibrary.wiley.com\/doi\/10.1111\/evj.14127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,28]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1111\/evj.14127"],"URL":"https:\/\/doi.org\/10.1111\/evj.14127","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/EVJ.14127\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.14127\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.14127\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.14127\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.14127\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.14127\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.14127\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EVJ.14127\/v3\/decision1","asserted-by":"object"}]},"ISSN":["0425-1644","2042-3306"],"issn-type":[{"value":"0425-1644","type":"print"},{"value":"2042-3306","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,28]]},"assertion":[{"value":"2023-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}