{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T23:50:55Z","timestamp":1789861855236,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,5,27]],"date-time":"2013-05-27T00:00:00Z","timestamp":1369612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Biopsy specimens from 23 early stage and 19 tumor\u2010stage mycosis fungoides (MF) patients were evaluated for miR\u2010155 expression by real\u2010time qualitative PCR and compared with 15 biopsy specimens from patients with T\u2010cell\u2010rich inflammatory skin diseases. Significant upregulation of miR\u2010155 was found in MF tumors compared with both early\u2010stage MF lesions and controls. There was no difference in miR\u2010155 expression between early\u2010stage and inflammatory dermatoses. Using laser capture microdissection, it was found that miR\u2010155 was significantly higher in the lymphoma cells in tumor stage compared with the intraepidermal lymphocytes in early stage. In contrast, there was no difference in miR\u2010155 expression between the intraepidermal lymphocytes and the dermal lymphocytes in early\u2010stage MF. These findings suggest that although miR\u2010155 expression cannot serve to discriminate early\u2010stage MF from inflammatory dermatoses; however, it is involved in the switch from the indolent early stage into the aggressive tumor stage of the disease.<\/jats:p>","DOI":"10.1111\/exd.12161","type":"journal-article","created":{"date-parts":[[2013,4,29]],"date-time":"2013-04-29T08:10:36Z","timestamp":1367223036000},"page":"431-433","source":"Crossref","is-referenced-by-count":42,"title":["miR\u2010155 is involved in tumor progression of mycosis fungoides"],"prefix":"10.1111","volume":"22","author":[{"given":"Lilach","family":"Moyal","sequence":"first","affiliation":[{"name":"Department of Dermatology Rabin Medical Center Beilinson Hospital Petach Tikva Israel"},{"name":"Laboratory for Molecular Dermatology Felsenstein Medical Research Center\u2010Tel Aviv University Petach Tikva 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